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Application of the Thorpe—Ziegler reaction for the synthesis of functionalized thiophenes, thienopyrimidines, and thienotriazines

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Abstract

Approaches to the synthesis of 3-aminothiophene-2,4-dicarboxylic acid derivatives and to their conversions into thieno[3,4-d]pyrimidines, thieno[3,4-d]-1,2,3-triazines, and thieno[3,2-d]pyrimidines are developed.

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Authors and Affiliations

  1. State Scientific Center of the Russian Federation “Organic Intermediate Products and Dyes Institute” (NIOPIK), 1/4 ul. Bol"shaya Sadovaya, 103787, Moscow, Russian Federation

    S. A. Ryndina, A. V. Kadushkin & V. G. Granik

  2. Center of Drug Chemistry, All-Russian Research Chemical Pharmaceutical Institute, 7 Zubovskaya pl., 119815, Moscow, Russian Federation

    N. P. Solov"eva

Authors
  1. S. A. Ryndina
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  2. A. V. Kadushkin
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  3. N. P. Solov"eva
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  4. V. G. Granik
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Ryndina, S.A., Kadushkin, A.V., Solov"eva, N.P. et al. Application of the Thorpe—Ziegler reaction for the synthesis of functionalized thiophenes, thienopyrimidines, and thienotriazines. Russian Chemical Bulletin 51, 854–859 (2002). https://doi.org/10.1023/A:1016049204323

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