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Antitumour activity of transition metal complexes with the thiosemicarbazone derived from 3-acetylumbelliferone

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Abstract

Metal complexes of a new thiosemicarbazone derived from 3-acetylumbelliferone (HL) have been prepared and characterized. The complexes have the general formula ML2 · nH2O where MII = Co, Ni, Cu and Zn; n = 0 and 2. The ligand and its complexes have been studied for their possible antitumour activity against HL-60 human leukemia in vitro.

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Wang, M., Wang, LF., Li, YZ. et al. Antitumour activity of transition metal complexes with the thiosemicarbazone derived from 3-acetylumbelliferone. Transition Metal Chemistry 26, 307–310 (2001). https://doi.org/10.1023/A:1007159301849

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