Abstract
The common etiological agents of onychomycosis are dermatophytes, molds and yeasts. A mycological nail investigation of onychomycosis using direct microscopy and culture was conducted by the Mycology Unit, Department of Medical Microbiology, University of Malaya from March 1996 to November 1998. The study involved 878 nail clippings or subungal scrapings from subjects with onychomycosis. On direct microcopy examination, 50% of the specimens were negative for fungal elements. On culture, 373 specimens had no growth; bacteria were isolated from 15 nail specimens. Among the 490 specimens with positive fungal cultures, 177 (36.1%) were dermatophytes, 173 (35.5%) were molds and 130 (26.5%) were Candida. There were 2% (10/490) mixed infections of molds, yeasts and dermatophytes. Trichophyton rubrum (115/177) and Trichophyton mentagrophytes (59/177) were the main dermatophytes isolated. The molds isolated were predominantly Aspergillus niger (61/173), Aspergillus nidulans (30/173), Hendersonula toruloidea (26/173) and Fusarium species (16/173). 96.9% of the Candida species identified were Candida albicans.
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References
Zaias N. Onychomycosis. Arch Derm 1972; 105: 263–274.
Basnerjee U, Sethi M, Pasricha JS. Study of onychomycosis in India. Mycoses 1990; 33(7-8): 411–415.
Ramani R, Srinivas CR, Ramani A, Kumari TG, Shivananda PG. Molds in onychomycosis. Int J Dermatol 1993; 32(12): 877–878.
Lim J T-E, Hock CC, Chee LG. Dermatophytes and nondermatophyte onychomycosis in Singapore. Australas J Dermatol 1992; 33(3): 159–163
Clayton YM. Clinical and mycological diagnostic aspects of onychomycosis and dermatomycoses. Clin Expt Dermatol 1992; 17(suppl): 37–40.
Baran R, Tosti A, Piraccini BM. Uncommon clinical patterns of Fusarium nail infection: report of three cases. Br J Dermatol 1997; 136: 424–427.
Tosti A, Piraccini BM, Stinchi C, Lorenzi S. Onychomycosis due to Scopulariosis brevicaulis: clinical features and response to systemic antifungals. Br J Dermatol 1996; 135(5): 799–802.
Baran R. Proximal subungual candida onychomycosis. An unusual manifestation of chronic mucocutaneous candidosis. Br J Dermatol 1997; 137: 286–288.
English MP. Nails and fungi. Br J Dermatol 1976; 94: 697–701.
Gupta AK, Horgan-Bell CB, Summerbell RC. Onychomycosis associated with Onychocola canadensis: ten case reports and a review of the literature. J Am Acad Dermatol 1998; 39(3): 410–417.
Kotrajaras R, Chongsathien S, Rojanavanich V, Buddhavadhikrai P, Viriyayudhakom S. Hendersonula toruloidea infection in Thailand. Int J Dermatol 1988; 27: 391–395.
Walshe MM, English MP. Fungi in nails. Br J Dermatol 1966;78: 198–207. McAleer R. Fungal infections in the nails in Western Australia. Mycopathologica 1981; 73: 115-120.
Sigler L, Carmichael JW. Taxonomy of Malbranchea and some other hyphomycetes with arthroconidia. Mycotaxon 1976; 4(2): 349–488.
Campbell MC, Stewart JL. The Medical Mycology Handbook. New York: John Wiley & Sons, 1980.
Gentles JC. Laboratory investigations of dermatophyte infections of nails. Sabouraudia 1971; 9: 149–152.
English MP, Atkinson R. An improved method for the isolation of fungi in onychomycosis. Br J Dermatol 1973; 88: 237–241.
Blecher P, Korting HC. A new combined diagnostic approach to clinically and microscopically suspected onychomycosis unproven by culture. Mycoses 1993; 36(9-10): 321–324.
Elewski BE. Diagnostic techniques for confirming onychomycosis. J Am Acad Dermatol 1966; 35(3): S6–9.
Tosti A, Piraccini BM, Stinchi C, Lorenzi S. Onychomycosis due to Scopulariopsis brevicaulis: clinical and response to systemic antifungals. Br J Dermatol 1996; 135(5): 799–802.
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Ng, K., Saw, T., Madasamy, M. et al. Onychomycosis in Malaysia. Mycopathologia 147, 29–32 (1999). https://doi.org/10.1023/A:1007044720147
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DOI: https://doi.org/10.1023/A:1007044720147