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“Unexplained” Delayed Death From Fungal Meningitis After Meningioma Resection
Published online by Cambridge University Press: 18 September 2015
Abstract
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Background
Progressive deterioration and ensuing death following a neurosurgical procedure often represents a diagnostic challenge to the team responsible for patient care. Many, but not all, causes are treatable if a diagnosis is made early.
Methods
A 69-year-old woman who died 6 weeks post-operatively following a meningioma resection is reported. An initial routine post-operative course became complicated by progressive neurological deterioration 3–4 weeks later. Despite extensive investigation she died 6 weeks post-operatively without a diagnosis.
Results
Autopsy demonstrated extensive Candida meningitis. A review of the literature demonstrates this to be a reported complication in high risk patients, difficult to diagnose, but treatable when identified.
Conclusions
Fungal meningitis should be high in the differential diagnosis in the post-operative patient with delayed, unexplained neurological deterioration, especially when associated with negative CSF cultures.
- Type
- Original Articles
- Information
- Copyright
- Copyright © Canadian Neurological Sciences Federation 1995
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