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Clearance of antibiotics from the intestines after termination of antibiotic decontamination

Published online by Cambridge University Press:  15 May 2009

D. van der Waaij ,
J. E. C. Lekkerkerk-van der Wees  and
P. J. Heidt
D. van der Waaij
Affiliation:
Radiobiological Institute TNO, 151 Lange Kleiweg, Rijswijk (Z.H.), The Netherlands
J. E. C. Lekkerkerk-van der Wees
Affiliation:
Radiobiological Institute TNO, 151 Lange Kleiweg, Rijswijk (Z.H.), The Netherlands
P. J. Heidt
Affiliation:
Radiobiological Institute TNO, 151 Lange Kleiweg, Rijswijk (Z.H.), The Netherlands
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Summary

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The clearance of neomycin and kanamycin from the intestines after stopping oral supply has been determined in mice. Both antibiotics, although given in different doses, were excreted in essentially the same way; the clearance being a little faster than logarithmically in both cases. The importance of this observation with regard to isolation and the moment of reconventionalization is discussed.

Type
Research Article
Information
Journal of Hygiene , Volume 73 , Issue 3 , December 1974 , pp. 409 - 414
Copyright
Copyright © Cambridge University Press 1974

References

REFERENCES

Abrams, G. D. & Bishop, J. E. (1966). Effect of the normal microbial flora on the resistance of the small intestine to infection. Journal of Bacteriology 92, 1604.CrossRefGoogle ScholarPubMed
Abrams, G. D. & Bishop, J. E. (1967). Effect of the normal microbial flora on gastrointestinal motility. Proceedings of the Society for Experimental Biology and Medicine 126, 301.CrossRefGoogle ScholarPubMed
Goss, W. A. & Cimijotti, E. B. (1968). Evaluation of an automatic diluting device for microbiological applications. Applied Microbiology 16, 1414.CrossRefGoogle ScholarPubMed
Waaij, D. van der, Vries, J. M. de & Lekkerkerk, J. E. C. (1970). Eliminating bacteria from monkeys with antibiotics. In: Infections and Immunosuppression in Subhuman Primates, p. 21. Copenhagen; Munksgard.Google Scholar
Waaij, D. van der & Andreas, A. H. (1971 a). Prevention of airborne contamination and cross-contamination in germ-free mice by laminar flow. Journal of Hygiene, 69, 83.CrossRefGoogle ScholarPubMed
Waaij, D. van der, Berghuis-de Vries, J. M. & Lekkerkerk-Van der Wees, J. E. C. (1971 b). Colonization resistance of the digestive tract in conventional and antibiotic-treated mice. Journal of Hygiene 69, 405.CrossRefGoogle ScholarPubMed
Waaij, D. van der, Vries, J. M. de & Lekkerkerk, J. E. C. (1972). Colonization resistance of the digestive tract and the spread of bacteria to the lymphatic organs in mice. Journal of Hygiene 70, 335.CrossRefGoogle Scholar