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Effect of diets low in calcium and phosphorus on the development of growing lambs

Published online by Cambridge University Press:  27 March 2009

A. C. Field ,
N. F. Suttle  and
D. I. Nisbet
A. C. Field
Affiliation:
Moredun Research Institute, Edinburgh EH1l 7JH
N. F. Suttle
Affiliation:
Moredun Research Institute, Edinburgh EH1l 7JH
D. I. Nisbet
Affiliation:
Moredun Research Institute, Edinburgh EH1l 7JH
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Summary

Five groups of four 8-week-old Blackface lambs were used to compare the effects of dietary deficiencies of calcium and/or phosphorus: four were given for 16 weeks a semi-purified diet low in Ca (0·07 %) and P (0·13 %), either unsupplemented (LCaLP) or supplemented with 0·3 % Ca (NCaLP), 0·3 % P (LCaNP) or both (NCaNP), and the remaining group was slaughtered initially.

The only clinical abnormality observed was twisting of the forelegs in group LCaLP. Food intake was depressed by 26 % in LCaNP group, by 41·5 % in NCaLP group but was largely unaffected in group LCaLP. Apparent D.M. digestibility was lower for group NCaLP (57·7 %) than for other groups (61·2 %). Differences in live weight and body fat reflected the differences in food intake between treatments but the weights of fat-free body components were lowest in the groups given low P diets.

The LCaNP diet decreased plasma Ca and increased plasma P but the NCaLP diet had the opposite effects. The LCaLP diet had no effect on plasma Ca and decreased plasma P less than the NCaLP diot.

The three mineral deficient diets caused equally marked decreases in Ca and P retention but did not induce negative balances; they also impaired the quality of bone in the tibia and lumbar vertebra, by reducing both the amount of bone matrix and the degree to which it was mineralized, and produced histological lesions of rickets and osteoporosis. Diets low in P caused a marked fall in Mg content of the skeleton.

Urolithiasis was common in lambs given diets adequate in P.

Type
Research Article
Information
The Journal of Agricultural Science , Volume 85 , Issue 3 , December 1975 , pp. 435 - 442
Copyright
Copyright © Cambridge University Press 1975

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References

REFERENCES

Balch, C. C. & Campling, R. C. (1962). Regulation of voluntary food intake in ruminants. Nutrition Abstracts and Reviews 32, 669–86.Google ScholarPubMed
Beeson, W. M., Johnson, R. F., Bolin, P. W. & Hickman, C. W. (1944). The phosphorus requirement for fattening lambs. Journal of Animal Science 3, 63–70.CrossRefGoogle Scholar
Benzie, D., Boyne, A. W., Dalgarno, A. C, Duckwokth, J., Hill, R. & Walker, D. M. (1960). Studies of the skeleton of the sheep. IV. The effects and interactions of dietary supplements of calcium, phosphorus, cod liver oil and energy, as starch, on the skeleton of growing Blackface wethers. Journal of Agricultural Science, Cambridge 54, 202–21.CrossRefGoogle Scholar
Boelter, M. D. D. & Greenberg, D. M. (1941). Severe calcium deficiency in growing rats. 1. Symptoms and pathology. Journal of Nutrition 21, 61–74.CrossRefGoogle Scholar
Clayden, E. C. (1952). A discussion on the preparation of bone sections by the paraffin wax method with special reference to the control of decalcification. Journal of Medical Laboratory Technology 10, 103–23.Google Scholar
Coons, S. L. (1957). The analysis of covariance as a missing plot technique. Biometrics 13, 387–405.CrossRefGoogle Scholar
Dutt, B. & Sawhney, P. C. (1965). Experimental calcium deficiency rickets in lambs. Indian Journal of Veterinary Science 35, 345–9.Google Scholar
Ewer, T. K. (1951). Rickets in sheep. 1. The experimental production of rickets in young sheep. British Journal of Nutrition 5, 287–300.CrossRefGoogle ScholarPubMed
Field, A. C. (1969). Urinary calculi in ruminants. Proceedings of the Nutrition Society 28, 198–203.CrossRefGoogle ScholarPubMed
Field, A. C., Suttle, N. F. & Gunn, R. G. (1968). Seasonal changes in the composition and mineral content of the body of hill ewes. Journal of Agricultural Science, Cambridge 71, 303–10.CrossRefGoogle Scholar
Fiske, C. A. & Subbarow, Y. (1925). The colorimetrio determination of phosphorus. Journal of Biological Chemistry 66, 375–400.CrossRefGoogle Scholar
Fitch, L. W. N. (1943). Osteodystrophic diseases of sheep in New Zealand. I. Bickets in hoggets: with a note on the aetiology and definition of the disease. Australian Veterinary Journal 19, 2–20.CrossRefGoogle Scholar
Franklin, M. C. (1934–1935). An investigation of the nutritional and biochemical effects of a low-calcium diet on sheep. University of Cambridge Institute of Animal Pathology 4, 111–78.Google Scholar
Harrison, M. &. Fraser, R. (1960). Bone structure and metabolism in calcium-deficient rats. Journal of Endocrinology 21, 197–205.CrossRefGoogle ScholarPubMed
Hemingway, R. G. (1963). Experimental production of phosphorus deficient rickets in young lambs. Proceedings of the Nutrition Society 22, xvi–xvii.Google Scholar
Hodge, R. W., Pearce, G. R. & Tribe, D. E. (1973). Calcium requirements of the young lamb. I. Effects of different intakes of dietary calcium on liveweight gain, bone development, and blood serum calcuim levels. Australian Journal of Agricultural Research 24, 229–36.CrossRefGoogle Scholar
McRoberts, M. R., Hill, R. & Dalgarno, A. C. (1965). The effects of diets deficient in phosphorus, phosphorus and vitamin D, or calcium, on the skeleton and teeth of the growing lamb. Journal of Agricultural Science, Cambridge 65, 1–10.CrossRefGoogle Scholar
Martin, C. J. & Pierce, A. W. (1934). Studies on the phosphorus requirements of sheep. I. The effect on young Merino sheep of a diet deficient in phosphorus but containing digestible proteins and vitamins. Bulletin of Council for Scientific and Industrial Besearch, No. 77, 5–44.Google Scholar
Neuman, W. F. & Neuman, M. W. (1958). The Chemical Dynamics of Bone Mineral. Chicago: The University of Chicago Press.Google Scholar
Nordin, B. E. C. (1960). Hyperparathyroidism, osteomalacia and osteoporosis. Clinical endocrinology 12, 233–58.Google Scholar
Palmer, H. (1970). Osteodystrophic diseases of sheep: the osteodystrophy of calcium deficiency. Ph.D. Thesis, University of Melbourne.Google Scholar
Pellegrino, E. D. & Biltz, R. M. (1968). Bone carbonate and the Ca to P molar ratio. Nature, London 219, 1261–2.CrossRefGoogle ScholarPubMed
Preston, R. L. & Pfander, W. M. (1964). Phosphorus metabolism in lambs fed varying phosphorus intakes. The Journal of Nutrition 83, 369–78.CrossRefGoogle ScholarPubMed
Stewart, J. (1934–1935). The effects of phosphorus deficient diets on the metabolism, blood and bones of sheep, with special reference to conditions existing in Great Britain. University of Cambridge Institute of Animal Physiology 4, 179–205.Google Scholar
Suttle, N. F. & Field, A. C. (1968). Effect of intakes of copper, molybdenum and sulphate on copper metabolism in sheep. 1. Clinical condition and distribution of copper in blood of the pregnant ewe. Journal of Comparative Pathology 78, 351–62.CrossRefGoogle Scholar
Suttle, N. F. & Field, A. C. (1969). Studies on magnesium in ruminant nutrition. 9. Effect of potassium and magnesium intakes on development of hypomagnesaemia in sheep. British Journal of Nutrition 23, 81–90.CrossRefGoogle ScholarPubMed
Sykes, A. R., Nisbet, D. I. & Field, A. C. (1973). Effects of dietary deficiencies of energy, protein and calcium on the pregnant ewe. V. Chemical analysis and histological examination of some individual bones. Journal of Agricultural Science, Cambridge 81, 433–40.CrossRefGoogle Scholar
Termine, E. D. & Posner, A. R. S. (1967). Amorphous/crystalline inter-relationship in bone mineral. Calcified Tissue Research 1, 8–23.CrossRefGoogle Scholar
Tomas, F. M. (1973). Parotid salivary secretion in sheep. Its measurement and influence on P in rumen fluid. Quarterly Journal of Experimental Physiology 58, 131–8.CrossRefGoogle Scholar
Young, V. R., Richards, W. P. C., Lofgreen, G. P. & Luick, J. R. (1966). Phosphorus depletion in sheep and the ratio of calcium to phosphorus in the diet with references to calcium and phosphorus absorption. British Journal of Nutrition 20, 783–94.CrossRefGoogle ScholarPubMed