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Seroprevalence of Chlamydia pneumoniae infections in otolaryngeal diseases

Published online by Cambridge University Press:  29 June 2007

Kazuhiro Hashiguchi ,
Hiroshi Ogawa  and
Yukumasa Kazuyama
Kazuhiro Hashiguchi*
Affiliation:
ENT Division, Kitasato Institute Hospital, Tokyo.
Hiroshi Ogawa
Affiliation:
ENT Division, Kitasato Institute Hospital, Tokyo.
Yukumasa Kazuyama
Affiliation:
Research and Development Centre of Hygienic Science, Kitasato University.
*
K. Hashiguchi, ENT Division, Kitasato Institute Hospital, 5-9-1, Shirogane, Minato-ku, Tokyo 108, Japan.
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Abstract

We studied the seroprevalence of antibodies to Chlamydia pneumoniae, the third species of chlamydia, in patients with acute infections in otolaryngeal sites. The patients were divided into five diagnostic groups, i.e. sinusitis, otitis media, tonsillitis, laryngitis and bronchitis group. Antibodies were measured by the microimmunofluorescent method. Antibodies confirming past infection with C. pneumoniae were found 46.2 per cent of the patients in the diagnostic groups and 44.7 per cent of the subjects in the control group. The difference between these two groups was not statistically significant. Acute or recent antibodies were detected in 10.5 per cent (2/19) of these patients with sinusitis, 19.2 per cent (10/52) of those with tonsillitis, 23.5 per cent (8/34) of those with otitis media, 18.2 percent (6/33) of those with laryngitis and 22.8 percent (13/57) of those with bronchitis, whereas only one member of the control group had acute antibodies. These data suggested that C. pneumoniae is an important and common pathogen of otolaryngeal disease.

Keywords

Chlamydia infectionsOtolaryngologic diseases
Type
Main Articles
Information
The Journal of Laryngology & Otology , Volume 106 , Issue 3 , March 1992 , pp. 208 - 210
Copyright
Copyright © JLO (1984) Limited 1992

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