Hostname: page-component-76fb5796d-skm99 Total loading time: 0 Render date: 2024-04-27T16:35:09.116Z Has data issue: false hasContentIssue false

Two malignant melanomas in skin and tonsil during consecutive pregnancies

Published online by Cambridge University Press:  29 June 2007

Alice Walsted
Affiliation:
Departments of Oto-rhino-laryngology and Pathology,Gentofte University Hospital, DK-2900 Hellerup, Denmark
Jens Thomsen*
Affiliation:
Departments of Oto-rhino-laryngology and Pathology,Gentofte University Hospital, DK-2900 Hellerup, Denmark
P. L. Nielsen
Affiliation:
Departments of Oto-rhino-laryngology and Pathology,Gentofte University Hospital, DK-2900 Hellerup, Denmark
*
Jens Thomsen, M.D., ENT Department, Gentofte University Hospital, DK-2900 Hellerup, Denmark.

Abstract

A patient is described with two primary malignant melanomas which developed during consecutive pregnancies four years apart. The first melanoma was of the cutaneous nodular type located on the arm. The second, of the superficial spreading type, was located in the oral mucosa near the right tonsil. The influence of pregnancy on the development and outcome of malignant melanomas is discussed, and the risk of a subsequent pregnancy is emphasised.

Type
Clinical Records
Copyright
Copyright © JLO (1984) Limited 1989

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

Batsakis, J. G. (1979) Tumors of the Head and Neck. 2nd. Ed., Baltimore, Williams & Wilkins Co.Google Scholar
Bork, K., Brauninger, W., Czarnetzki, B. M., Addicks, B., Paul, E. and Glitsch, M. (1985) Schwangerschaft nach malignen Melanom. Deutsche Medizinisch Wochenschrift, 110: 13191323.Google Scholar
Ellis, D. L., Wheeland, R. C. and Solomon, H. (1985) Estrogen and progesterone receptors in melanocytic lesions. Archives of Dermatology, 121: 12821285.Google Scholar
Holman, C. D. J., Armstrong, B. K. and Heenan, P. J. (1984) Cutaneous malignant melanoma in women: Exogenous sex hormoes and reproductive factors. British Journal of Cancer, 50: 673680.Google Scholar
Hormia, M. and Vuori, E. E. J. (1969) Mucosal melanoma of the head and neck. Journal of Laryngology and Otology, 83: 349354.CrossRefGoogle Scholar
Houghton, A. N., Flannery, J. and Viola, M. V. (1981) Malignant melanoma of the skin occurring during pregnancy. Cancer, 48: 407410.3.0.CO;2-L>CrossRefGoogle Scholar
Karakousis, C. P., Lopez, R. E., Bhakoo, H. S., Rosen, F., Moore, R. and Carlson, M. (1980) Estrogen and progesterone receptors and tamoxifen in malignant melanoma. Cancer Treatment Reports, 64: 819827.Google ScholarPubMed
McCarty, K. S. Jr., Wortman, J., Strowers, S., Lubahn, D. B., McCarty, K. S. Sr. and Siegler, H. F. (1980) Sex steroid receptor analysis in human melanoma. Cancer, 46: 14631470.Google Scholar
Moeller, D., Ipsen, L. and Asschenfeldt, P. (1986) Fatal course of malignant melanoma during pregnancy with dissemination to the products of conception. Acta Obstetrica Gynecologica Scandinavica, 65: 501502.Google Scholar
Pennington, D. G. (1983) Multiple primary melanomas in pregnancy: a case report. British Journal of Plastic Surgery, 36: 260261.Google Scholar
Reintgen, D. S., McCarty, K. S., Vollmer, R., Cox, E. and Siegler, H. F. (1985) Malignant melanoma and pregnancy. Cancer, 55: 13401344.Google Scholar
Riberti, C., Marola, G. and Bertani, A. (1981) Malignant melanoma: the adverse effect of pregnancy. British Journal of Plastic Surgery, 34: 338339.Google Scholar
Schwartz, B. K., Zashin, S. J., Spencer, S. K., Mills, L. E. and Sober, A. J. (1987) Pregnancy and hormonal influences on malignant melanoma. Journal of Dermatologic Surgery and Oncology, 13: 276281.Google Scholar
Seddan, J. M., Maclaughlin, D. T., Albert, D. M., Graougdas, E. S. and Ference, M. (1982). Uveal melanomas presenting during pregnancy and the investigation of oestgrogen receptors in melanomas. British Journal of Ophthalmology, 66: 695704.Google Scholar
Shiu, M. H., Schottenfeld, D., MaClean, B. and Fortner, J. G. (1976) Adverse effect of pregnancy on melanoma. A reappraisal. Cancer, 37: 181187.Google Scholar
Sutherland, C. M., Loutfi, A., Mather, F. J., Carter, R. D. and Krementz, E. T. (1983a) Effect of pregnancy upon malignant melanoma, Surgery, Gynecology and Obstetrics, 157: 443446.Google Scholar
Sutherland, C. M., Wittliff, J. L., Fuchs, A. and Mabie, W. C. (1983b) The effect of pregnancy on hormone levels and receptors in malignant melanoma. Journal of Surgical Oncology, 22: 191192.Google Scholar
Svane-Knudsen, V. (1957) Primary, malignant melanoma of the tonsil. Acta Otolaryngologica, 47: 364368.Google Scholar