Hostname: page-component-848d4c4894-pftt2 Total loading time: 0 Render date: 2024-06-01T02:04:09.843Z Has data issue: false hasContentIssue false
  • English
  • Français

The persistance of drug resistant Escherichia coli strains in the majority faecal flora of calves

Published online by Cambridge University Press:  19 October 2009

M. Hinton ,
P. D. Rixson ,
Vivien Allen  and
A. H. Linton
M. Hinton
Affiliation:
Department of Veterinary Medicine, University of Bristol, Langford House, Langford, Avon BS18 7DU
P. D. Rixson
Affiliation:
Department of Veterinary Medicine, University of Bristol, Langford House, Langford, Avon BS18 7DU
Vivien Allen
Affiliation:
Department of Veterinary Medicine, University of Bristol, Langford House, Langford, Avon BS18 7DU
A. H. Linton
Affiliation:
Department of Microbiology, Medical School, University of Bristol, Bristol BS8 1TD
Rights & Permissions [Opens in a new window]

Summary

Core share and HTML view are not available for this content. However, as you have access to this content, a full PDF is available via the ‘Save PDF’ action button.

Two groups of calves, one of three and the other of two animals, were purchased in markets and reared initially on a commercial veal unit for 1 month and 4 months respectively. They were then moved to the Veterinary School, Langford, and kept for a further 6 and 4 months respectively. The animals were sampled weekly and a continual turnover in the strains forming the majority Escherichia coli faecal flora was demonstrated for all calves. Antibacterial-drug resistance, as measured by an Antibiotic Resistance Index (ARI), increased after arrival on the veal unit and persisted at high levels during the whole of their stay. After moving to Langford the ARI fell. Initially there was a reduction in the average number of resistance determinants per resistant strain and then, after a delay of up to 8 weeks, by an increase in the proportion of isolates that were fully sensitive. The source of the sensitive strains was not ascertained, although their appearance was not associated specifically with either weaning or turning out to pasture.

Type
Research Article
Information
Journal of Hygiene , Volume 93 , Issue 3 , December 1984 , pp. 547 - 557
Copyright
Copyright © Cambridge University Press 1984

References

Hartley, C. L., Howe, K., Linton, A. H., Linton, K. B. & Richmond, M. H. (1975). Distribution of R plasmids among O-antigen types of Escherichia coli isolated from human and animal sources. Antimicrobial Agents and Chemotherapy 8, 122–131.CrossRefGoogle ScholarPubMed
Hinton, M., Allen, V. M.& Linton, A. H. (1982). The biotyping of Escherichia coli isolated from healthy farm animals. Journal of Hygiene 88, 543–555.CrossRefGoogle ScholarPubMed
Hinton, M.& Linton, A. H. (1983). Antibacterial drug resistance among Escherichia coli isolated from calves fed on a milk substitute diet. Veterinary Record 112, 567–568.CrossRefGoogle ScholarPubMed
Howe, K.& Linton, A. H. (1976). The distribution of O-antigen types of Escherichia coli in normal calves, compared with man, and their plasmid carriage. Journal of Applied Bacteriology 40, 317–330.CrossRefGoogle ScholarPubMed
Linton, A. H. (1977). Antibiotic resistance: the present position reviewed. Veterinary Record 100, 354–360.CrossRefGoogle Scholar
Linton, A. H., Howe, K.& Osborne, A. D. (1975). The effects of feeding tetracycline, nitrovin and quindoxin on the drug-resistance of coli-aerogenes bacteria from calves and pigs. Journal of Applied Bacteriology 38, 255–275.CrossRefGoogle ScholarPubMed
Linton, A. H., Timoney, J. F.& Hinton, M. (1981). The ecology of chloramphenicol resistance in Salmonella typhimurium and Escherichia coli in calves with endemic salmonella infection. Journal of Applied Bacteriology 50, 115–129.CrossRefGoogle ScholarPubMed