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Alcohol dehydrogenase activity in Drosophila melanogaster: a quantitative character

Published online by Cambridge University Press:  14 April 2009

R. D. Ward
R. D. Ward
Affiliation:
Department of Genetics, University of Cambridge, Cambridge CB4 1XH, U.K.
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Alcohol dehydrogenase activity in Drosophila melanogaster may be considered as a quantitative character, since it shows many features typically associated with such traits. Although strains with the electrophoretically fast phenotype generally have activities greater than those with the slow phenotype, presumably reflecting differences in the nucleotide sequences of the structural alleles, within each electrophoretic class there is considerable variation in activity. The expression of the structural gene, in terms of ADH activity, is to some extent regulated by its genetic background. Strains homozygous for particular structural alleles respond to divergent directional selection for ADH activity. Modifiers have been located to the X, second and third chromosomes.

Type
Research Article
Information
Genetics Research , Volume 26 , Issue 1 , August 1975 , pp. 81 - 93
Copyright
Copyright © Cambridge University Press 1975

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