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Sterilising effects of benzyl-l,3-benzodioxoles on the tsetse fly Glossina morsitans morsitans Westwood (Diptera: Glossinidae)

Published online by Cambridge University Press:  10 July 2009

P. A Langley ,
M. A Trewern  and
L. Jurd
P. A Langley
Affiliation:
Tsetse Research Laboratory, University of Bristol, Longford, Bristol BS18 7DU, UK
M. A Trewern
Affiliation:
Tsetse Research Laboratory, University of Bristol, Longford, Bristol BS18 7DU, UK
L. Jurd
Affiliation:
USDA, AR, Western Regional Research Centre, Berkeley, California 94710, USA*
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Abstract

Three benzyl-l,3-benzodioxoles and three benzylphenols were tested for their ability to sterilise Glossina morsitans morsitans Westw. following topical application in acetone. Two of the former compounds, 5-ethoxy-6- (4-methoxyphenylmethyl)-l,3-benzodioxole and 5-ethoxy-6-[l-(4-meth-oxyphenyl)ethyl]-l,3-benzodioxole, caused total sterility in females at a dose of 10 μg per fly, and remained effective even after one year's storage at 4°C. Dose-fecundity data indicate a reduction to 50% fecundity (ED50) was achieved with 2·5 μg of the former or 0·5 μg of the latter per fly. An ED90 of 8·5 μg and 2·5 μg, respectively, is indicated. The latter compound reduced the survival of treated females and males and surviving males were incapable of inseminating even though copulation appeared normal. The effects on female survival and fecundity, of feeding the compounds at 0·25 and 1·0% in blood, were variable, owing to their low solubility and variations in the size of blood-meals. The highest doses of the former compound led to ovarian atrophy in females, which can be described as an effect on fecundity. Lower doses induced sterility through egg death and atrophy after ovulation. The latter compound acted more rapidly than the former, preventing ovulation of the first mature oocyte in a higher proportion of flies. The activity of these compounds, which were derived by modification of plant materials, and are non-mutagenic, renders them likely candidates for evaluation as contact insecticides for Glossina in the field.

Type
Original Articles
Information
Bulletin of Entomological Research , Volume 72 , Issue 3 , September 1982 , pp. 473 - 481
Copyright
Copyright © Cambridge University Press 1982

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