Clinical indications: what is the evidence?
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Diagnostic Performance of PET/MRI in Breast Cancer: A Systematic Review and Bayesian Bivariate Meta-analysis
2023, Clinical Breast CancerCitation Excerpt :MRI can clearly and finely display tissues and organs' morphology and anatomical structure and provide a multidimensional and comprehensive analysis of physiological, biochemical, and organ functions in living organisms.3 Because of the superior soft-tissue resolution (high signal-to-noise ratios and contrast-to-noise ratios) in diagnosing breast lesions, breast MRI has higher sensitivity and specificity than other conventional imaging examinations in screening for breast cancer in high-risk women, assessing the extent of preoperative breast cancer lesions, and screening for postoperative recurrence of high-risk breast cancer.4-7 18F-FDG PET, as a molecular imaging diagnostic tool, is more specific but less sensitive for diagnosing primary breast tumors than breast MRI.8
Impact of Advancing Technology on Diagnosis and Treatment of Breast Cancer
2018, Surgical Clinics of North AmericaCitation Excerpt :This study suggests that screening women of average risk with breast MRI is useful. Given its high sensitivity and ability to detect clinically, mammographically, and sonographically occult breast cancers36,42,56–58 the use of breast MRI has increased over the past decade.36,40,43,59 However, the specificity of breast MRI is moderate, and breast MRI is limited owing to the high cost, long examination time, long interpretation time, and lower availability compared with mammography and ultrasound examination.60
What is the yield of breast MRI in the assessment of palpable breast findings?
2017, Clinical RadiologyCitation Excerpt :Its main advantage is high sensitivity in detecting breast cancer6,7; however, besides its high cost, its main drawback is low specificity, which may lead to unnecessary examinations and biopsies.8–10 Breast MRI has been shown to be useful for a number of indications including screening high-risk patients and determining extent of disease in patients with invasive carcinoma or ductal carcinoma in situ (DCIS)11–14; however, the use of breast MRI as a problem-solving tool, including evaluation of palpable breast masses, has not been supported in the literature.10,15–18 Despite this lack of data, MRI is occasionally used in practice, after standard imaging (mammography and breast US) has failed to characterise a palpable finding.
MR Imaging: Future Imaging Techniques
2017, Radiologic Clinics of North AmericaCitation Excerpt :New hybrid techniques, such as PET–MR imaging, have also generated significant interest, and are discussed elsewhere in this issue. Given its high sensitivity and ability to detect cancers occult to mammography, ultrasound, and clinical breast examination,1–7 breast MR imaging use has increased over the past decade, particularly for high-risk screening. Limitations of this technique, however, include higher cost, longer examination time, longer interpretation time, and lower availability when compared with mammography and ultrasound.3
Diagnostic applications of nuclear medicine: Breast cancer
2022, Nuclear Oncology: From Pathophysiology to Clinical Applications