Alpha-glutathione transferases in HCV-related chronic hepatitis: a new predictive index of response to interferon therapy?
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2020, Microbial PathogenesisCitation Excerpt :Also can correlate this product with the group in which antibiotics were used, where it showed the same or better results, as observed in the F + NGLM4 group, the group with the least GST activity. This result may indicate lesser degrees of infection and toxicity [34–36]. Associated with the yellowish discoloration of the liver of chicks and high levels of TBARS activity, was also observed greater levels of triglycerides and cholesterol in the intoxicated groups, suggesting a direct connection, because increases in TBARS levels can cause fatty liver.
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2019, Fish and Shellfish ImmunologyCitation Excerpt :Therefore, the highest expression of HaGSTκ1 in the liver and kidney tissues is suggestive of their possible involvement in the xenobiotic detoxification process. GSTs are multifunctional enzymes [62] that show an immune response against bacterial [63] and viral infections [64]. Previous studies have revealed a considerable upregulation in the expression of several GST types during an immune challenge in seahorse (Hippocampus abdominalis) [49], black rockfish (Sebastes schlegelii) [56], disk abalone (Haliotis discus discus) [19], and the Manila clam (Ruditapes philippinarum) [50,51,65].
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