Case reportMicroscopy and latex antigen negative cryptococcal meningitis
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2007, Veterinary Clinics of North America - Small Animal PracticeCitation Excerpt :In practice, the proteinaceous background and surrounding inflammatory cells are usually just as useful for demonstrating the capsule and are less prone to artifact (Fig. 4). In addition, the lack of a capsule does not rule out Cryptococcus spp, because there are acapsular strains that can be difficult to differentiate from Candida spp [22]. When examining a cytologic preparation, it is important to keep in mind that fungi can occasionally present with atypical morphology.
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