Long-Term Follow-Up of Term Neonates with Perinatal Asphyxia
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Long-term neuropsychological and behavioral outcome of mild and moderate hypoxic ischemic encephalopathy
2022, Early Human DevelopmentEEG phase-amplitude coupling to stratify encephalopathy severity in the developing brain
2022, Computer Methods and Programs in BiomedicineNeurological and developmental outcomes following neonatal encephalopathy treated with therapeutic hypothermia
2021, Seminars in Fetal and Neonatal MedicineCitation Excerpt :This highlights both the difficulty in reliably identifying a “mild” category to include in studies and the problems clinicians have in selecting neonates for treatment that has become standard of care. In their studies from the 1970's, Robertson and Finer identified challenges in the categorisation of the stage of NE [16] that have not been resolved. Agreement on clear definitions for trial entry is urgently needed before trials of TH in neonates with mild NE are planned.
Cooling in mild encephalopathy: Costs and perils of therapeutic creep
2021, Seminars in Fetal and Neonatal MedicineCitation Excerpt :These data are similar to the observation by Finder et al. were the Bayley Scale of Infant and Toddler Development composite scores in cooled infants with mild encephalopathy (8/55) were not different to the ones who were not cooled (47/55) [36]. Landmark long term follow-up studies in the ‘90s involving 66 infants with mild encephalopathy by Robertson et al. did not find any major neurological impairment at 3.5 years [38]. At 8 years of life, the school performance of these children was similar to that of their peers [39].
High-risk babies and neurodevelopmental outcome
2021, Diagnosis, Management and Modeling of Neurodevelopmental Disorders: The Neuroscience of DevelopmentWavelet-based neurovascular coupling can predict brain abnormalities in neonatal encephalopathy
2021, NeuroImage: Clinical
Support provided by the Northern and Central Alberta Regional Perinatal Program and the Glenrose Rehabilitation Hospital, Edmonton, Alberta, Canada. Material referenced from work done under an operating grant from the Canadian National Health Research Development Program, #6609-1479-R.