Elsevier

Clinical Biochemistry

Volume 18, Issue 1, February 1985, Pages 20-26
Clinical Biochemistry

Inter-laboratory quality control of estrogen and progesterone receptor assays in breast cancer tissue using lyophilised cytosols

https://doi.org/10.1016/S0009-9120(85)80018-7Get rights and content

In 1981 a quality control (QC) program for estrogen and progesterone receptor assays was organized among six laboratories in Ontario, Canada. Twenty-three vials of lyophilised cytosol prepared from human breast tumor tissues were analysed by each laboratory over a two-year period. Samples of each batch of QC material were analysed at least twice: either in the same batch or on separate occasions.

The present study

  • a)

    demonstrates the stability of the QC material.

  • b)

    defines the relative accuracy of the receptor assays, and

  • c)

    provides estimates of within-batch and between-batch precision of the receptor assays.

References (25)

  • JacobsonBE

    Investigation of estrogen-receptor protein in human mammary carcinoma for the establishment of a routine clinical assay

    Can J Med Tech

    (1981)
  • McGuireWL et al.

    Evaluation of estrogen receptor assays in human breast cancer tissue

    Cancer Res

    (1977)
  • Cited by (0)

    1

    Kingston General Hospital, Kingston, Ontario.

    2

    Dept. of Surgery, University of Toronto, Toronto, Ontario.

    3

    Ottawa Civic Hospital, Ottawa, Ontario.

    4

    Sunnybrook Hospital, Toronto, Ontario.

    5

    Victoria Hospital, London, Ontario.

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