Pituitary metastasis is rare in clinical work, and we collected 10 cases.
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We performed a literature review to summarize the characteristics of pituitary metastasis.
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We are following the patients after surgery to know their prognosis.
Objective
This study aimed to summarize the diagnosis, therapy, and prognosis of pituitary metastasis.
Methods
Ten patients from the Department of Neurosurgery of the Peking Union Medical College Hospital from April 1997 to August 2014 were retrospectively analyzed.
Results
The participants included 7 males (70%) and 3 females (30%), with an average age of 60.4 years. The most common initial clinical feature was visual disability (50%). The postoperative pathology reports indicated 1 case (10%) of metastatic large-cell pulmonary carcinoma, 2 cases (20%) of metastatic small cell pulmonary carcinoma, 2 cases (20%) of clear cell renal carcinoma metastasis, and 5 cases (50%) of metastasis of adenocarcinomas from different areas. All the patients underwent a thorough follow-up, and the average survival was 144 days.
Conclusions
Pituitary metastasis is a rare disease. Its diagnosis depends on the clinical manifestations and radiologic results. The primary therapeutic method is surgery and subsequent radiotherapy and chemotherapy; however, the prognosis of this disease is poor.
Key words
Diagnosis
Operation
Pituitary metastasis
Prognosis
Therapy
Abbreviations and Acronyms
CT
Computed tomography
MRI
Magnetic resonance imaging
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Conflict of interest statement: The authors declare that the article content was composed in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.