Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontology
Oral and maxillofacial surgeryHistological and molecular temporomandibular joint analyses after mandibular advancement surgery: study in minipigs
Section snippets
Animals
Eighteen 15-month-old male minipigs (Minipig BR-1),27, 28, 29, 30 weighing 35 kilograms each, were used. The animals were kept individually and fed with pig food (S4, Bravisco, Bastos-São Paulo, Brazil) in a daily amount equivalent to 2% of the animal's weight and water ad libitum. The animals were randomly divided into 3 groups (6 animals each): Group I (control), nonoperated animals; Group II, animals submitted to surgical advancement surgery and osteosynthesis by bicortical screws; and Group
Descriptive histological analysis
Group I presented characteristics of normality. The articular disk was composed of dense connective tissue, rich in collagen fibers, and with a thin aspect in the central area. The synovial membrane covered the internal surface of the TMJ fibrous capsule and the margins of the articular disk. The condyle showed a more regular and symmetrical shape than in both experimental groups. The presence of areas with secondary condylar cartilage indicated that the animals were at the final growth phase.
Discussion
The present study demonstrated that there were histological and molecular differences in the TMJs among the groups. Some authors described condylar alterations after surgeries for DDFS treatment.36, 37, 38 Clinical signs as dental and bone recurrences may occur depending on the severity of the alterations.15
The images obtained from the histological analysis demonstrated characteristics of normality for the condyles of Groups I (control) and III (miniplates), although signs of bone remodeling
Conclusions
Considering the methodology used, the results indicated that rigid fixation (bicortical screws) resulted in higher levels of condylar remodeling, but with indications of a less intense inflammatory process, when compared with the semi-rigid fixation technique (miniplates). Therefore, the use of rigid fixation seems to transmit higher impact of the masticatory forces to the TMJs than semi-rigid fixation. Further clinical studies are necessary to confirm these data.
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Cited by (6)
Osseous alterations in the condylar head after unilateral surgical directional change in rabbit mandibular condyles: Preliminary study
2014, Journal of Cranio-Maxillofacial SurgeryHistologic and tomographic analyses of the temporomandibular joint after mandibular advancement surgery: study in minipigs
2009, Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology and EndodontologyCitation Excerpt :Regardless of the technique used, mandibular position changes after surgical advancement surgery can generate condylar alterations.15,21,49,50 However, the literature15,16,21,51,52 demonstrates that postsurgical condylar alterations are more evident when bicortical screws are used for fixation, as was revealed here. The results indicated that bicortical screw fixation resulted in more pronounced alterations in the shape of the condyles.
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