Indian jujube a potential fruit tree to improve the livelihood

Graphical abstract

rainfall, high temperature, high wind, and a wide variety of soils like limestone, laterite, and sandy (Lim, 2012;Singh et al., 2020). It is a hardy tree that can withstand extreme climatic conditions and yield well; thus, its cultivation attracts farmers worldwide. Ziziphus mauritiana can grow in soil with neutral or slightly alkaline pH (7.5). However, it can quickly acclimatize in shallow to deep soil like clayey, sandy, and rocky. However, the most favourable soil is sandy loam for good plant growth (Pareek, 2013). It is a spiny shrub or small tree reaching up to 3-15 m with a trunk of about 40 cm or more in diameter.
The branches have stipular spines, and the ends are bent downwards. The bark is dark grey or dull black. The leaves are simple, ovate or oblong, rounded at both ends, and arranged alternately in two rows. The leaves are adaxially shiny green and abaxially whitish tomentose. The leaves have three basal nerves and two stipular spines; one is long and straight, and the other is short, bent back, and frequently brown (Orwa et al., 2009;Lim, 2012;C.A.B.I., 2022). The inflorescence is axillary cyme, 1-2 cm long, with minute greenish-yellow hermaphrodite flowers. The flowers have 3-8 mm long pedicles, five petals, and a calyx with five deltoid lobes. The fruit is an edible drupe, globose or ovoid, initially green, then it becomes yellow, orange, or red on ripening.The fruits of the wild type can grow to a diameter of 2 cm, whereas those of the cultivated type can grow up to or more than 5 cm longer. The fruit has a tuberculate, irregularly furrowed stone-like seed consisting of 6 mm long elliptical red-brown kernels, 1-2 in number. The pictorial representation of the tree, leaves, flower, raw, and ripen fruit are represented (Fig. 1).The fruit is edible and eaten fresh, dried like dates, salted, or pickled. The fruit provides a high source of carotene, vitamins A and C, and fatty acids. Fruits can be macerated in water to create a cool, refreshing drink, and young leaves are cooked as a vegetable in Indonesia (Orwa et al., 2009;Lim, 2012). The wood obtained for Indian jujube is reddish-brown in colour, fine-textured, rugged, and robust. Thus, it is used to construct houses and tools in rural regions. It also makes good firewood (Heuzé et al., 2019).
Indian jujube can be propagated from seeds, in situ grafting, and budding using rootstocks. According to reports, the fruit has more minerals, vitamin C, and protein than apples and mangoes while having a higher phosphorus and iron content than oranges (Khera and Singh, 1976;Hussain et al., 2021). It is a rich source of dietary fibre, reducing and non-reducing sugar, calcium, magnesium, potassium, sodium, and phosphorus. The fresh ripened fruit pulp contains carotenoids, fluorides, pectin, citric acid, thiamine, riboflavin, niacin, and ascorbic acid. Maleic acid, oxalic acid, and quercetin are reportedly present in the fleshy part of the fruit (Prakash et al., 2020). Studies revealed that seeds, fruits, bark, leaves, and flowers possess important pharmacological properties. Phytochemical analysis revealed the presence of different bioactives belonging to the category of alkaloids, flavonoids, glycosides, saponins, terpenoids, tannins, fatty acids, and phytosterols (Goyal et al., 2012;Najafi, 2013;Mbahi et al., 2018;Prakash et al., 2020;Butt et al., 2021). An ethnomedicinal study of Ziziphus mauritiana revealed that the seed kernels have sedative properties and are used as poultices to stop vomiting and nausea and even relieve abdominal pain during pregnancy. Its formulations are used for wound healing and antidote to aconite poisoning. In the Indian state of Bihar, the seeds are used to treat diarrhea. Leaves of the plant are regarded as an astringent and have diaphoretic properties. Formulation of leaves are used to treat typhoid in children. The bark decoction treats gingivitis, boils, diarrhea, and dysentery. In Ayurveda, the roots of Z. mauritiana are used in curing cough, headache, and biliousness. The root powder is applied over the wound and ulcer to get relief. The leaves have anti-obesity and    (Xu et al., 2020).

Nutraceutical properties
Ziziphus mauritiana is a multipurpose plant known to have potential pharmacological activities. Many studies were conducted to understand the different biological properties of varying tree parts, including antioxidant activity, anticancer, antimicrobial, and antidiabetic studies. The plant is a good source of polyphenols, flavonoids, alkaloids, glycosides, tannins, and saponins. Reports indicate that the DPPH and H 2 O 2 scavenging activity of 250 lg/ mL fruit extract of Ziziphus mauritiana were 79.5 ± 0.83 % and73.4 ± 0.45 %, respectively (Dureja and Dhiman, 2012). San et al. (2013) reported that the total phenolic and flavonoid content of 50% ethanolic extract of Ziziphus mauritiana was found to be 27.6 2 ± 1.43 mg gallic acid equivalent (GAE)/g extract and 0.74 ± 0.03 mg quercetin equivalent (QE)/g extract respectively. The report suggests that the methanolic extract of Apple Ber (hybrid Ziziphus mauritiana) exhibited the highest antioxidant activity, followed by ethyl acetate extract. Higher equivalent dry weight exhibited stronger antioxidant defences against DPPH free radicals (Nigam, 2018). Akanda and Hasan, (2021) reported that the total phenol content was higher in the seed extract. Compared to seed extract, stem extract has higher flavonoids. Z. mauritiana stems bark and seed extract showed high antioxidant capacity. Further, the cytotoxicity effect of Ziziphus mauritiana seed and stem bark extract in brine shrimp lethality bioassay indicates that the seed extract (LC 50 = 1.46 lg/mL and LC 90 = 2.48 lg/mL) was found to be most cytotoxic than stem bark extract.
Reports suggest that using an alpha-amylase inhibition assay, the saponin extract of Ziziphus mauritiana leaves demonstrated its significant anti-diabetic properties. The percentage of extract inhibition ranged from 21.2 % to 97.09 % in the alpha-amylase inhibition experiment (Dubey et al. 2019). Perumal et al., (2012) indicate that linoleic acid oxidation was effectively inhibited by Ziziphus mauritiana leaf extract, followed by stem bark extract. Further, the cytotoxicity was determined against the Vero cell line, and the IC 50 value was reported to be 59.78 and 61.47 lg/mL.
As per reports, the methanolic fruit extract of Ziziphus mauritiana was found to exhibit the highest cytotoxic effect (70-80%) against HeLa cells (cervical carcinoma cells), which was determined by MTT assay (Beg et al., 2016). As per reports, Ziziphus mauritiana fruit extract was found to have a significant antibacterial effect on Escherichia coli and Staphylococcus aureus, exhibiting a zone of inhibition of 11 mm and 8 mm, respectively. In contrast, fruit extract in chloroform exhibited a zone of inhibition of 10 mm and 12 mm against E. coli and S. aureus, respectively (Beg et al., 2016). Reports suggest that the Z. mauritiana fruit extractmediated silver nanoparticles at 40 lg/mL dosage exhibited an antibacterial effect against Bacillus subtilis, Shigella boydii, Escherichia coli, and Salmonella enteritidis by forming an inhibition zone of 14 mm, 10 mm, 9 mm and 8 mm respectively. Further, the antifungal activity of Z. mauritiana fruit extract silver nanoparticles was examined against Aspergillus niger and Trichoderma species at different concentrations. Results revealed that significant antifungal activity was observed against both strains at a dose of 60 lg/ mL of Ag/AgCl-NPs by inducing 100% growth inhibition in the culture plates (Kabir et al., 2020). A study on supplementing Ziziphus mauritiana leaf powder with Nile Tilapia (Oreochromis niloticus) prevented Aeromonas hydrophila infection. It increased the expression of the genes for lysozyme and superoxide dismutase. It enhanced the activity of serum lysozyme and liver antioxidant enzymes. Moreover, the fish's survival rate was significantly higher than the control. The fishes fed with 10 g/kg of the dietary supplement containing Ziziphus mauritiana leaf showed improved histopathological parameters that were altered due to Aeromonas hydrophila infection concerning the liver, spleen, and kidney, and  (Ji et al., 2012) Mauritine L (Panseeta et al., 2011) Cyclopeptide Alkaloid Antimycobacterial &antiplasmodial activities (Panseeta et al., 2011) Ceanothic acid (Panseeta et al., 2011) Triterpenoid Antiplasmodial and antimycobacterial activities (Panseeta et al., 2011) N. Kumar Sishu, U. Das and C. Immanuel Selvaraj Saudi Journal of Biological Sciences 30 (2023) 103769 Table 2 Pharmacological aspects of extracts, isolates and nanoparticle from different parts of Ziziphus mauritiana.

Seed Aqueous ethanolic extract
Antihyperglycemic activity A dose of 800 mg/kg seed extract and 10 mg/kg glyburide significantly reduced blood glucose level, weight loss, and mortality rate. It improved peripheral insulin sensitivity, enhanced glucose/insulin metabolism, or increased islet of Langerhans insulin release. The results showed that the dosages enhanced glucose tolerance, increasing peripheral glucose utilization in diabetic and non-diabetic mice.

Anticancer activity
The extract showed the highest cytotoxic effect against HL-60 cells with an IC 50 value of 40 lg/mL. Moreover, the flow cytometric analysis determined by staining with annexin V-FITC and PI exhibited that the seed extract induced 18.8% and 61.2% apoptosis at five lg/mL and 80 lg/mL, leading to cell death.

Mishra et al., 2011
Leaf Ethanol & ethyl acetate extract Hepatoprotective activity Ethyl acetate extract (400 mg/kg) and ethanol extract (300 mg/kg) reduced the elevated levels of enzyme markers such as AST, ALT, ALP, and total bilirubin. It increased the total protein levels in Wistar rats with paracetamol-induced hepatotoxicity. Further, histological studies showed reduced inflammation and fatty vacuoles in the liver. Immunostimulatory and anti-allergic activity It increased antibody production and was known to be mitogenic for lymphocytes and splenocytes. It also caused macrophages to produce more lysosomal enzymes, which indicates that both the humoral and cellular arms of immunity are stimulated. It completely prevented anaphylactic shock and Arthus reaction in the in vivo model.  (Table 1) and different pharmacological aspects of Ziziphus mauritiana (Table 2). These studies make Ziziphus mauritiana a promising subject for researchers to study the chemical constituents and extracts of its different parts to understand its use in drug development and mechanism of action concerning various diseases.

Potential industrial use
According to Nyanga et al. (2013), Z. mauritiana fruit is essential in terms of nutrition, economics, and society in Zimbabwe. Research studies on chemical analysis of the nutritive composition of Ziziphus mauritiana seed revealed that the seed powder is rich in proteins and essential amino acids; moreover, the composition (g/100 g dry weight) of seed powder showed 4.21 ± 0.30 g/100 g of moisture, 2.79 + 0.27 g/100 g of ash, 36.10 ± 0.57 g/100 g of proteins, 11.04 ± 0.88 g/100 g of crude fibres, 27.40 ± 0.11 g/100 g of lipids, and 21.26 ± 0.63 g/100 g of carbohydrates. Mineral composition studies revealed that the seed has a high content of minerals which include 154.79 ± 10.50 g/100 g of Na, 589.08 ± 10.69 g/100 g of K, 585.43 ± 41.29 g/100 g of P, 6.23 ± 0.12 g/100 g of mg, 3.52 ± 0. 05 g/100 g of Zn, 1.15 ± 0.14 g/100 g of Mn, and1.21 ± 0.15 g/100 g of Fe (Yerima& Adamu, 2011). Reports suggest that the Ziziphus mauritiana leaves powder showed different parameters of nutritional composition in percentage (w/w), which include total ash at 8.02%, acid insoluble ash at 2.72%, Water Soluble Ash at 4.11%, Moisture Content at 7.62%, Crude fibres at 13.08%, and Volatile matters with 0.19% (Gupta et al., 2012). The calcium and phosphorus concentrations range in Ziziphus mauritiana (Thai Apple Ber) fruits was 20.48 to 23.50 mg/100 g and 24.08 to 25.25 mg/100 g, respectively. Moreover, the ascorbic acid content varies from 25.60 to 27.87 mg/100, and the vitamin A content varies from 14.80 to 16.08 mg/100 g of fruit (Langthasa et al., 2021). Bioadhesive polymers that adhere to biological surfaces are one of many methods of drug delivery for oral diseases. The adhesion between two materials, where the mucosa is one of the biological surfaces, is called mucoadhesive. The availability of drugs through mucosal surfaces is wider and faster. It enhances medication concentration, permeability, delivery, and tissue protection. Mucoadhesion occurs when interfacial forces hold the drug together on the mucus layer of the mucous membranes. Bioavailability is enhanced by localizing the drug using the mucoadhesive delivery method. Polymers interact with the tissue mucosa, extending contact time and the effect. The mucoadhesive delivery method strengthens patient adherence, facilitates drug administration, improves accessibility, and prolongs residence time, which increases drug absorption and efficacy. Several reports indicate that the fruits and seeds of Ziziphus mauritiana can be employed in producing mucoadhesive materials suitable for drug delivery (Singh et al., 2013;Hamedi et al., 2016;Ray et al., 2021). According to the report, proximate composition and mineral elements analysis on the fruits of the Ziziphus mauritiana plant showed that the fruit contains moisture (5. 16 ± 0.29 mg/100 g), ash (6.16 ± 0.29 mg/100 g), sodium (7.67 ± 0. 138 mg/100 g), potassium (306.67 ± 11.55 mg/100 g), calcium (0. 33 ± 0.003 mg/100 g), magnesium (0.16 ± 0.005 mg/100 g), and phosphorus (1.58 ± 3.34 mg/100 g)in dry weight, respectively (Keta, 2017). The nutritional composition of Ziziphus mauritiana fruit per 100 g edible portion is mentioned (Table 3).
A report suggests that the ethanol-water extract of Ziziphus mauritiana fruit obtained from Ultrasound-assisted extraction (UAE) exhibited high antioxidant activity. It can be used as a natural antioxidant in oil and oil-based products as it reduces the oxidation of oil-based products in comparison to synthetic antioxidants such as tertiary-butylhydroquinone, butylated hydroxytoluene and butylated hydroxyanisole used in the study (Delfanian et al., 2016). Vinegar obtained from the fruit pulp of Z.mauritiana contains many antioxidants and exhibits high antioxidant activity (Vithlani and Patel, 2010). Ziziphus mauritiana ground seed crude fat was saponified, and then its methyl esters were synthesized and analyzed by GC-MS. The GC-MS reading showed the presence of hexadecanoic acid (7.2%), eicosanoic acid (2.1%), docosanoic acid (1.5%), octadecanoic acid (6.9%), 7-octadecenoic (55.2%), 11-eicosenoic acid (1.9%), and 9,12-octadecenoic acid (25.3%). The saturated and unsaturated fatty acid percentage ratio was 5.3%. Moreover, the GC-MS analysis of an unsaponifiable fraction of seed oil showed the presence of squalene (14%), stigmasterol (23.6%), d-4-Sitosterol-3-one (6.8%), campesterol (5.8%), c-tocopherol (4.3%). Thus, Z. mauritiana is a good oil source rich in monosaturated fatty acids and can be used to produce food products (Memon et al., 2012). Saponins, known to bind cholestrol are also abundant in Z. mauritiana seeds and these can lower the cholestrol level. It also possesses the beneficial phytochemical betulinic acid, which could help develop new medicine formulations. This versatile plant has a variety of possible economic uses, including fuel, fodder, and beekeeping . Several studies have highlighted the economic importance and various usage of fruits, seeds, and leaves of Z. mauritiana, which can be used further at a larger scale in the industrial sector to produce different products (Table 4).

Climate resilience
According to reports, the Indian native fruit Ziziphus mauritiana is incredibly drought-resistant. It makes up a large portion of the indigenous vegetation in the ''Thar desert" of India. It may be successfully grown even in the most vulnerable tropical and subtropical ecosystems. India has planted 90,000 acres of enhanced Ber trees, with an average production of 8.34 tonnes per hectare (Awasthi and More, 2008). Studies revealed that cultivators in the northwest part of India preferred growing Z. mauritiana or Ber for its ability to withstand harsh climatic and soil conditions. Even though there are challenges in growing ber regarding access to the markets, poor soil quality, high salinity, and poor access to fresh water, 80% of farmers have been practicing cultivating ber as a crop since the plants require much less atten- Table 3 Nutritional composition of Ziziphus mauritiana fruitper 100 g edible portion (EP) (Pareek, 2013;Stadlmayr et al., 2013;Prakash et al., 2020).

Constituents
Fruit per 100 g EP

Part of the tree/ component of Ber Uses Property Reference
Fruit (mucilage) Production of natural gum The mucilage obtained from the fruit pulp of Indian jujube had pseudo-plastic properties, water holding capacity (11.77 g dry weight), and good oil absorption ability (4.96 g oil/g dry weight); thus, it can be employed in the production of natural gums-related products.

Thanatcha and Pranee, 2011
Fruit pulp Ethanol production Conditions like a temperature of 30°C, pH of 6, and yeast (8.0 g) or fruit pulp (20 g) were ideal for ethanol generation. A concentration of 63 g/L of ethanol was produced in such parameters. Saccharomyces cerevisiae (NA33) had to be added to boost the rate and yield of fermentation because the control (without S. cerevisiae) vessel revealed a low fermentation rate. Togarepi et al., 2012 Fruit Production of fermented beverages It was found S. cerevisiae strains and non-Saccharomyces species like Pichia kudriavzevii, Saccharomycopsisfibuligera, and Pichia fabianii that have been isolated from Ziziphus mauritiana fruit and their traditionally fermented fruit pulp are suitable starter cultures for production of flavour compounds for fermented products. Nyanga et al., 2013 Gum isolated from fruit pulp Mucoadhesive material The yield % of gum isolated from the fruit pulp was 38.56% at room temperature; it dissolves readily in hot water and partially in cold water. The gum has better mucoadhesive strength than Carbopol 934 and Hydroxypropyl methylcellulose (HPMC) and thus can replace synthetic mucoadhesive polymers and polysaccharides. Ray et al., 2021 Seed (mucilage) Mucoadhesive tablet The mucilage fraction obtained from the seed of Ziziphus mauritiana showed substantial mucoadhesion strength. It was found that 3% w/v mucilage has shown mucoadhesion strength comparable to 1 % w/v Carbopol 934P. Thus, it can be employed in forming additives to design oral mucoadhesive tablets. Gangurde et al., 2012 Fruit extract Prevention of oxidation of oilbased products Extract (600 ppm) added to soyabean oil exhibited more thermo-oxidative stability of soybean oil, low carbonyl compounds formation in soyabean oil during the frying process, reduced level of peroxide value in oil, reduced production of conjugated compounds, reduction in the hydrolysis of oil and maximum oxidative stability index of soyabean oil in comparison to synthetic antioxidants. Delfanian et al., 2016 Dietary fibres from fruit peel Use in food product The dietary fibres from the fruit peel by the freeze-drying process exhibited effective DPPH scavenging properties, vitamin C content, total phenolic content, and higher oil-holding capacity. Thus, the dietary fibre fraction of Indian jujube can be employed in various food products.

Sarkar et al., 2022
Leaves Soap formulation For the formulation of antioxidant soap, 0.3% leaf extract of Ziziphus mauritiana was used as the foaming agent. The best soap formulated showed 1.09 g/mL of density, pH of 9.8, 25.50% of several fatty acids, 1.2462% of free fatty acid, 2.52% of neutral fatty, and foam stability of 83.95%.

Widyaningsih et al., 2022
Fruit pulp Food product (Biscuit) The fruit pulp can be used for making biscuits using the steamed sandwich method; the product was better with crude fibre, protein, and carbohydrates. Thus, the fruit pulp biscuit can fulfill nutritional requirements by serving as a useful food product. tion. However, the yield is affected; thus, it can be managed by adopting better agriculture technology . The report suggested that Z. mauritiana showed significant fruit yield after being grown under harsh conditions such as arid soil and irrigation done with brackish water containing a salt concentration of 3500 ppm. A study conducted from 2013 to 2018 observed that fruit yield increased over time, rising from its lowest point in the fruiting season of 2013-14 to its highest point in 2017-18. The highest yield/plant recorded was 55.66 kg/plant in 2017-18, followed by 44.95 kg/plant. After harvesting of fruits, pruning was found to be crucial every year (Pathan et al., 2020). It was reported that Ber (Ziziphus mauritiana L.) was cultivated in lysimeters artificially salinized with magnesium sulfate, sodium chloride, magnesium chloride, and calcium in salt tolerance. A salinity of 20 dSm À1 electrical conductivity was too high for any plants to survive. It was observed that with increasing salinity (15 dSm À1 ) while potassium concentration (425 mg/100 g dry weight) in leaf tissues dropped whereas, the level of sodium (1930 mg/100 g dry weight), calcium (2490 mg/100 g dry weight), Magnesium (1550 mg/100 g dry weight), and Chloride (1360 mg/100 g dry weight) concentrations significantly rose. While lower production and fruit set resulted from higher salinity, fruit quality was unaffected. The investigation's findings indicate that Ber can grow in saline soils with electrical conductivity (EC) up to 11.30 dSm À1 (Hooda et al., 1990). According to reports, hex-ose sugars were significantly higher during drought stress due to changes in sugar metabolism. This suggests that altered solute partitioning may play a significant role in Ziziphus mauritiana's ability to withstand drought. Further, it was observed that 0.7 MPa reduced osmotic potential at full turgor according to pressure-volume analyses. In contrast, leaves under drought stress had their osmotic potential reduced by $ 1 MPa at turgor loss. Along with osmotic adjustment, bulk tissue elastic modulus (wall rigidity) increased by 65% under progressive dryness, which led to turgor loss in both stressed and unstressed leaves at the same rate (Clifford et al., 1998).

Conservation and breeding efforts of Z. mauritiana
The researcher needs to familiarize themselves with the floral biology of the crop before beginning any breeding program. Depending on the type and agro-climatic conditions, the ber blossoming season in India extends from early June to late November. The length of the flowering period varied from 68 to 94 days overall, depending on the cultivar. The growth of the current season is mainly producing flowers. However, October is when most of the fruit sets. Most kinds do not produce fruit themselves (Pareek et al., 2007). Ber's breeding program's primary goals are to create cultivars with traits such as early maturity, plentiful yield, appealing fruit colour, smaller seed size, firm texture, high soluble con-   (Tables 5 and 6).

Breeding strategy for Z. mauritiana
Offspring trials that replicated across the environments range where Z. mauritiana is grown included many accessions. Selection of best promising accessions considering qualitative and quantities characters to improve production. Ensure control of pollination to improve the cross between the populations. After the cross-produced progeny can be replicated and evaluated to ensure that chosen trees ought to make up a sizable share of the breeding population. Vegetative propagate of the tree and domesticate the set of selected clones.

Livelihood generation
According to reports, Z. mauritiana thrives in the challenging conditions of the Thar Desert, including dry weather, arid soil, salinity stress, and inadequate water irrigation. Consequently, it will benefit the Thar people in combating climate change, food shortages, and hunger (Pathan et al., 2020). Once the fruit ripens, it is consumed raw in India. The fruit may also be used to produce pickles and can be properly dried out in the sun to extend its shelf life. The leaves are also valuable as fodder because of their nutritional richness and quick regeneration. According to research, silkworms are fed leaves as nourishment. For the lac insect, Kerria lacca, which feeds on the leaves' juice and coats them with an orange-red resin, Z. mauritiana is grown as a host plant. In baking and jam-making, fruit powder derived from Z. mauritiana is utilized. Green, unripe fruits make the sauce, pickles, and jellies (Goyal et al., 2012). As per reports, he primarily uses Z. mauritiana in nutrition, forage, and medicines. Its fruits are consumed fresh as such and processed into various products, such as porridge, traditional cake, jam, and alcoholic and non-alcoholic beverages. Under high heat and little rainfall, the tree thrives and produces well. Growing Households in arid and semi-arid areas may benefit from Z. mauritiana by having lessened food and financial insecurity, especially in light of recent climate change effects that have led hot, dry zones to spread out. For instance, in Zimbabwe, the fruit is picked in the Zambezi Valley in large numbers and marketed across the country and even beyond. (Maruza et al., 2017). Reports suggest that the lac insect strain, namely Kerria lacca (rangeeni and kusmi), can be cultivated on Z. mauritiana; it was observed that the productivity of lac is high, and there is no adverse effect on the tree if harvesting of crop, pruning, and coppicing is done appropriately. In India, 93 million Ber trees are available, and they can be employed for lac culture. Leaves of Z. mauritiana can be used as fodder since it contains high crude protein, crude fibre, starch, and minerals. The tree parts can be used as fuel as the sapwood has 4900 kcals/kg, and timber as the hardwood has a density of 535-1080 kg/m3 (Yogi et al., 2017). As per reports Z. mauritiana (Masau) fruits are consumed and sold for a profit in markets to generate an income in Zimbabwe. After expo-sure to the sun for a few hours, this is used to make a beverage called ''mahewu" in Zimbabwe (Nyanga et al., 2008). As per the report of Newaj et al., (2017) there are potential fodder treebased agroforestry systems, including Ziziphus mauritiana, that can boost production, positively affect microclimate, minimize soil degradation, restore soil fertility, and diversify income-generating opportunities.

Conclusions and future prospects
The whole plant of Ziziphus has greater utilization, either edible or inedible, and has been reported in different studies as represented in this review. The active constituents present in Ziziphus fruit possess anti-diabetic, anti-inflammatory, and anticancerous properties. For year-round availability, the fruits can be processed and dehydrated. They are the source of compounds such as rutin, ceanothic, and betulinic acid, which can treat various illnesses affecting human health. Ziziphin, Hyperoside, Phytol, and c-sitosterol may be extracted from leaves and used industrially.
Moreover, it provides a significant source of protein on a dryweight basis, making it a good choice for animal feed. Because of its high economic return, cheap cultivation costs, and greater tolerance to endure drought stress and soil alkalinity, Ziziphus is becoming increasingly popular among fruit farmers and may one day serve as a source to stop soil erosion and desertification. Under limited rainfall and high heat conditions, the tree thrives and produces well. Growing Z. mauritiana could solve food, nutritional, and economic problems, considering the current climate change effects that have caused the expansion of hot and dry zones. The tree can be used for many things, including making furniture, poles for different purposes, animal feed, medicines, nectar-producing flowers, and much more. The fruit can be processed into various goods, including non-alcoholic and alcoholic beverages, traditional cake, porridge, and jam, and is consumed raw, dry, or fresh. Jujube research should respond more precisely to business, markets, and government needs, and it may even actively develop and lead these demands. Research goals should be more advanced and diverse. Improved rootstock and germplasm evaluation and screening strategies must be adopted to establish high-efficiency propagation systems. Ensuring year-round supply needs to include a variety of cultivars with varying maturation periods, staggering in harvesting, dehydration, and long-distance cold transportation. Thus, it will be essential to focus on developing this crop soon to export it to the non-traditional source of income.