The aim of this study is to determine the relationship of 21st century skills on students’ attitudes and perceptions towards Physics. The samples in this study consisted of 760 form four secondary students in Selangor. The instruments used were adapted from 21st century skills that have been defined by enGauge 21st Century Skills. The results showed that students’ attitude towards Physics is at high level but students’ perceptions on teaching and learning of Physics is at the moderate level. Pearson coefficient correlation analysis showed that there was a significant positive and strong relationship of 21st century skills on students’ attitude towards Physics.
