Editorial
Adropin: A new regulatory peptide in cardiovascular endocrinology

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Funding

None.

Conflicts of interest

The authors declare that there are no conflicts of interest.

Cited by (19)

  • Neuroprotective effect of ischemic preconditioning via modulating the expression of adropin and oxidative markers against transient cerebral ischemia in diabetic rats

    2016, Peptides
    Citation Excerpt :

    Adropin is a recently identified regulatory protein that has been cited in the sustainment of energy homeostasis, insulin sensitivity and also nonmetabolic features that include regulation of endothelial function [4,28]. It is encoded by the Energy Homeostasis Associated Gene (Enho), which is expressed in the liver and as a neuropeptide in the brain [29,30]. The research has indicated that after being diagnosed with gestational diabetes mellitus during pregnancy, maternal and cord serum adropin concentrations can be significantly lower than control pregnant women [31].

  • Enho Mutations Causing Low Adropin: A Possible Pathomechanism of MPO-ANCA Associated Lung Injury

    2016, EBioMedicine
    Citation Excerpt :

    It showed that Enho was mainly regulated by miRNAs, along with the only gene, mitochondrial uncoupling protein 1 (UCP1), which is responsible for the nonshivering thermogenesis in brown adipose tissue (BAT) (Fig. 1j) (Fedorenko et al., 2012). Adropin cDNA from human, mouse, rat, and pig are similar (Goetze and Albrethsen, 2014). To investigate the possibility that adropin serves as an endogenous vasoprotective substance, we used AdrKO mice (Fig. 2a) for assessing the effect of adropin-deficiency on the formation of neointima or vasculitis.

  • Therapeutic effects of adropin on glucose tolerance and substrate utilization in diet-induced obese mice with insulin resistance

    2015, Molecular Metabolism
    Citation Excerpt :

    Adropin is a small peptide that has been linked to metabolic homeostasis and cardiovascular function [1–4].

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