Simultaneous acute presentation of generalized chorea and subacute combined degeneration secondary to vitamin B12 deficiency

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Highlights

  • Acute-onset chorea and haematological abnormalities should prompt vitamin B12 assessment.

  • Clinical screening for SCD should be warranted in patients with acute chorea.

  • Replacement therapy might achieve rapid improvement in cases with vitamin B12 deficit.

Section snippets

Declaration of interest

Carlos Estevez-Fraga has received educational grants from Zambon.

Juan Carlos Martínez-Castrillo has received honoraria for speaking at meetings sponsored by AbbVie, Allergan, Boehringer, GSK, Krka, Merz, Ipsen, Italfarmaco, Medtronic, TEVA, UCB, Zambon.

Elena Natera-Villalba, Beatriz Zarza Sanz, Fernando Acebrón Sánchez-Herrera, Fabio Ruiz-Gómez, Araceli Alonso Canovas and Iñigo Corral certify that they have NO affiliations with or involvement in any organization or entity with any financial

Financial disclosures

Carlos Estevez-Fraga has received educational grants from Zambon.

Juan Carlos Martínez-Castrillo has received honoraria for speaking at meetings sponsored by AbbVie, Allergan, Boehringer, GSK, Krka, Merz, Ipsen, Italfarmaco, Medtronic, TEVA, UCB, Zambon.

Funding sources

This research did not receive any specific grant from funding agencies in the public, commercial, or not-for-profit sectors.

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Acknowledgments

The authors want to thank Dr. Paul Zeun for English language editing.

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