Research LetterQuality of life, diet and exercise measurements in obese individuals with and without ventilatory failure
Introduction
Obesity is associated with reduced quality of life (QOL), particularly physical health. In addition obesity has been linked to reduced exercise and high calorie diet. We aimed to describe these factors in obese individuals with and without ventilatory failure, and investigate the hypothesis that ventilatory failure would have a negative impact on QOL.
Section snippets
Methods
QOL, diet and exercise were assessed as part of an open cross-sectional study of ventilatory failure in obese subjects referred either for assessment of sleep disordered breathing or bariatric surgery. The study was approved by the Oxford research ethics committee (Oxfordshire REC B 11/H0605/9). The study was registered prospectively with a global trials registry site (ClinicalTrials.gov, NCT01380418).
The SF-12 was completed; a validated questionnaire to assess QOL giving summary scores for
Results
77 (42 (54.5%) male) individuals with a mean age of 51.7 years (SD 8.9) and median BMI of 46.4 kg/m2 (IQR 39.2, 52.5) participated in the study. Median duration of actigraphy was 23.2 days (IQR 21.2, 23.4). Table: Results of SF-12, actigraphy, food frequency questionnaire and arterial blood gasses.Empty Cell N Study mean or median SD or IQR 95% confidence interval of difference from comparison mean p value PCS 58 38.0 11.3 −16.4, −11.3 <0.0001 MCS 58 41.2 10.6 −10.2, −5.0 <0.0001 Energy expenditure (kCal) 58 2977 566 Daily steps
Conclusions
Obesity had a large negative impact on both physical and mental QOL not reproducibly reported elsewhere. Ventilatory failure was only a weak predictor of mental, but not physical QOL scores. The majority of participants were sedentary and dietary calorie intake was higher than the recommended daily allowance for most women and a significant number of men. Actigraphy energy expenditure estimates exceeded patient reported dietary intake, which is probably due to patient underreporting. This
References (2)
- et al.
Is a raised bicarbonate, without hypercapnia, part of the physiologic spectrum of obesity-related hypoventilation?
Chest
(2015 Feb) - et al.
An assessment of the construct validity of the SF-12 summary scores across ethnic groups
J Public Health Med
(2001)
Cited by (0)
- 1
Joint first authors.