Molecular Cell
Volume 47, Issue 4, 24 August 2012, Pages 633-647
ResourceDNA Methylation Dynamics during In Vivo Differentiation of Blood and Skin Stem Cells
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Graphical Abstract
Highlights
► Genomic DNA methylation maps for 19 purified cell types of blood and skin lineages ► Myeloid transcription factors and binding sites become methylated in lymphoid cells ► Adult stem cells retain low DNA methylation at regulatory regions of other lineages ► Epigenome and transcriptome enable inference of the blood differentiation hierarchy
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These authors contributed equally to this work
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Present address: CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences, 1090 Vienna, Austria and Department of Laboratory Medicine, Medical University of Vienna, 1090 Vienna, Austria
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