Pre-Clinical ResearchIntracoronary Injection of In Situ Forming Alginate Hydrogel Reverses Left Ventricular Remodeling After Myocardial Infarction in Swine
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Key Words
biomaterials
heart failure
myocardial infarction
remodeling
Abbreviations and Acronyms
CT
computed tomography
ECG
electrocardiogram/electrocardiographic
ECM
extracellular matrix
LAD
left anterior descending
LV
left ventricle/ventricular
MI
myocardial infarction
MPG
myocardial perfusion grade
MR
mitral regurgitation
TFG
Thrombolysis In Myocardial Infarction flow grade
TIMI
Thrombolysis In Myocardial Infarction
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Supported by a research grant from BiolineRx, Jerusalem, Israel, and Ben-Gurion University of the Negev, Beer-Sheva, Israel. Drs. Leor and Cohen applied for a patent on injectable alginate for myocardial repair via Ben-Gurion University of the Negev, Beer-Sheva, Israel, and are advisers of BiolineRx, Jerusalem, Israel. Drs. Tuvia, Shaul, and Klapper are employees of BiolineRx, Jerusalem, Israel. Dr. Cohen holds the Claire and Harold Oshry Professor Chair in Biotechnology. Drs. Leor and Tuvia contributed equally to this work.
Copyright © 2009 American College of Cardiology Foundation. Published by Elsevier Inc. All rights reserved.