Research PaperTMJ DisordersThe use of SPECT/CT to assess resorptive activity in mandibular condyles
Section snippets
Study design and sample
This study was performed in accordance with the ethics protocols approved by the Ethics Committee of Keio University (approval number 20190319). Patients with CR due to either ICR or DJD, based on the diagnostic criteria reported by Peck et al.8 (“Expanding the taxonomy of the diagnostic criteria for temporomandibular disorders”), diagnosed between 2013 and 2019, were included in this study. Patients with CR due to inflammatory joint diseases including rheumatoid arthritis and infectious
Clinical data
The CR group comprised eight condyles from four patients with bilateral ICR, two condyles from two patients with unilateral ICR, and two condyles from one patient with bilateral DJD (12 condyles in seven patients). All of the CR group patients were female. The mean observational period (from T0 to T1) in the CR group was 14.1 months (Table 1).
Analysis of bone metabolism in the mandibular condyles
The weighted kappa statistic showed excellent inter-observer agreement between the two observers (κ = 0.954). Ten condyles were considered positive (score
Discussion
This study is novel in describing the behaviour of bone metabolism corresponding to resorptive changes in detail. The relationship between bone metabolism and the subsequent morphological changes in the mandibular condyles was investigated. It was found that positive 99mTc HMDP uptake in the condyle was associated with a decrease in condylar height and condylar volume. In contrast, negative 99mTc HMDP uptake reflected morphological stability of the condyles. In addition, the degree of 99mTc
Funding
None.
Competing interests
None declared.
Ethical approval
Ethical approval (No. 20190319) was given by the Ethics Committee of Keio University School of Medicine.
Patient consent
The institutional review board of the hospital waived the need for informed consent from the patients.
References (20)
- et al.
Condylar resorption
Oral Maxillofac Surg Clin North Am
(2007) Progressive condylar resorption: pathologic processes and imaging considerations
Semin Orthod
(2013)- et al.
Idiopathic condylar resorption
Br J Oral Maxillofac Surg
(2018) - et al.
Surgical management of idiopathic condylar resorption
Oral Maxillofac Surg Clin North Am
(2018) - et al.
Clinical value of 3D SPECT/CT imaging for assessing jaw bone invasion in oral cancer patients
J Craniomaxillofac Surg
(2019) - et al.
Subclassification of fractures of the condylar process of the mandible
Br J Oral Maxillofac Surg
(2005) - et al.
Management of dentoskeletal deformity due to condylar resorption: literature review
Oral Surg Oral Med Oral Pathol Oral Radiol
(2016) - et al.
Management-related outcomes and radiographic findings of idiopathic condylar resorption: a systematic review
Int J Oral Maxillofac Surg
(2015) - et al.
Idiopathic condylar resorption: a systematic review of etiology and management
Oral Surg Oral Med Oral Pathol Oral Radiol
(2020) - et al.
Idiopathic condylar resorption: a survey and review of the literature
J Oral Maxillofac Surg
(2018)
Cited by (2)
Accuracy of skeletal scintigraphy for the evaluation of mandibular growth disorders: a systematic review
2024, International Journal of Oral and Maxillofacial SurgeryConservative and minimally invasive approaches to control idiopathic condylar resorption: a scoping review
2023, International Journal of Oral and Maxillofacial Surgery