Saturday poster abstractSa1663 Self-Expandable Metal Stent Is a Valid Alternative in the Palliation of Gastric Outlet Obstruction Patients With High Karnofsky Performance Status
Introduction
Gastric outlet obstruction is commonly seen in patients with advanced pancreatic cancer, distal gastric cancer and periampullary carcinoma. Many of these patients tend to be poor candidates for palliative surgery. Alternatively, endoscopic placement of self-expandable metal stents (SEMS) has been increasingly used for these patients.
Section snippets
Aim
To evaluate the efficacy and safety of SEMS for patients with an indication of endoscopic palliative treatment of malignant gastric outlet obstruction.
Patients and Methods
A total of 39 consecutive patients with unresectable malignant gastroduodenal obstruction, who underwent endoscopic palliation through SEMS, between February 2010 and April 2012, were retrospectively studied. Clinical outcomes including tumor type, site of obstruction, success rate, Karnofsky performance status (KPS), gastric outlet obstruction scoring system of food intake (GOSS), complications and survival were evaluated.
Results
The mean age was 62.2 years-old (varying from 35 to 84 years-old) and 21 patients were female. Primary malignancy corresponded to: pancreatic cancer in 14, gastric cancer in 10, common bile duct cancer in 9, metastatic lesions in 3 (breast, kidney, lung), and colon cancer extrinsic compression in 2. The maximum oral intake before stenting was liquid diet in 37 patients and semisolid food in 2. Technical success rate of stenting was 100%. The stents were placed transpyloric in 36 patients and
Conclusions
1. SEMS is an efficient and safe alternative for patients with malignant gastric outlet obstruction; 2. A Karnofsky performance status ≥ 40 was associated to better GOSS after placement of SEMS for the palliation of malignant gastric outlet obstruction, while low KPS represents poor predictive factor of GOSS.