The fellows' corner
Guidewires in ERCP

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Wire specifications

The basic structure of the guidewire consists of a monofilament core with an outer coating. The core material for the monofilament is typically composed of nitinol, which has largely replaced stainless steel. The monofilament is covered with an outer sheath made of polytetrafluoroethylene (PTFE, or Teflon) or polyurethane, synthetic hydrophobic materials, enabling the smooth exchange of devices over the wire. The distal tip, or business end, of the guidewire is coated with an additional

Long-wire system

The need for the long wire at the inception of ERCP was dictated by the fact that this length was needed to exchange the various devices needed for the procedure.3 The endoscopic assistant requires training and experience to be adept at manipulating the guidewire. In addition, excellent communication is needed between the physician and the assistant. This may make using the long-wire system a challenge at facilities that do not have experienced staff available. Difficulties between physician

Safety considerations

The primary complication associated with guidewire use during ERCP is perforation. The main site at risk for guidewire-related perforation is the biliary tree. A large retrospective study of 6620 ERCPs identified 7 guidewire-related perforations.6 All were recognized during the procedure and were managed medically, with only 1 patient requiring a biliary stent. Concern for electrical injury transmitted from the cutting sphincterotomy wire to the guidewire is more of a historical concern because

Costs

All of the guidewires used in ERCP are disposable, single-use items. In many cases, there is no significant difference in price between the various lengths and diameters of the guidewires. However, the short-wire method is generally more expensive than the long-wire technique because of the relatively higher costs of the short-wire accessories, including balloons, baskets, stent deployment systems, and brushes, in comparison with their analogous counterparts in the traditional long-wire system.

Conclusion

Guidewires play a critical role in ERCP in cannulating the papillae, facilitating selective access to the desired duct, and enabling exchange of devices. They may also serve to reduce post-ERCP pancreatitis—one of the feared complications of the procedure. Although specific benefits are associated with both the short-wire and the long-wire systems, the key difference between them is the degree of physician control over the guidewire. Ultimately, the physician's experience and preferences with

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