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Hallucinogen persisting perception disorder after psilocybin consumption: a case study

Published online by Cambridge University Press:  16 April 2020

Marie-Laure Espiard
Affiliation:
Centre Esquirol, Centre Hospitalier Universitaire de Caen, 14033Caen cedex, France
Laurent Lecardeur
Affiliation:
Centre Esquirol, Centre Hospitalier Universitaire de Caen, 14033Caen cedex, France Groupe d’Imagerie Neurofonctionnelle, UMR 6198 CNRS, CEA, Universités de Caen et Paris 5, GIP Cyceron BP 5229, 14074Caen cedex, France
Pascale Abadie*
Affiliation:
Centre Esquirol, Centre Hospitalier Universitaire de Caen, 14033Caen cedex, France
Isabelle Halbecq
Affiliation:
Centre Esquirol, Centre Hospitalier Universitaire de Caen, 14033Caen cedex, France
Sonia Dollfus
Affiliation:
Centre Esquirol, Centre Hospitalier Universitaire de Caen, 14033Caen cedex, France Groupe d’Imagerie Neurofonctionnelle, UMR 6198 CNRS, CEA, Universités de Caen et Paris 5, GIP Cyceron BP 5229, 14074Caen cedex, France
*
*Corresponding author. Tel.: +33 2 31 06 44 28; fax: +33 2 31 06 49 55. E-mail address: abadie-p@chu-caen.fr (P. Abadie).
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Abstract

The recurrence of flashbacks without acute or chronic hallucinogen consumption has been recognized in the DSM IV criteria as the hallucinogen persisting perception disorder (HPPD). Perceptual disturbances may last for 5 years or more and represent a real psychosocial distress. We reported here a case of a 18-year-old young man presenting HPPD after a mixed intoxication with psylocibin and cannabis. This report shows symptomatic recurrences persisting more than 8 months. Various differential diagnoses were evoked and our therapeutic strategies were described.

Type
Case report
Copyright
Copyright ©Elsevier SAS 2005

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References

Abraham, H.D., Mamen, A.LSD-like panic from risperidone in post-LSD visual disorder. J. Clin. Psychopharmacol. 1996; 16: 238241CrossRefGoogle ScholarPubMed
Aldurra, G., Crayton, J.W.Improvement of hallucinogen persisting perception disorder by treatment with a combination of fluoxetine and olanzapine: case report. J. Clin. Psychopharmacol. 2001; 21: 343344CrossRefGoogle ScholarPubMed
American Psychiatric Association Diagnostic and statistical manual of mental disorders. 4th ed Washington, DCAmerican Psychiatric Association 1994Google Scholar
Halpern, J.H., Pope, H.G.Hallucinogen persisting perception disorder: what do we know after 50 years? Drug Alcohol Depend. 2003; 69: 109119CrossRefGoogle ScholarPubMed
Horowitz, M.J.Recurrent intrusive images after the use of LSD. Am. J. Psychiatry 1969; 126: 565569CrossRefGoogle ScholarPubMed
Lerner, A.G., Gelkopf, M., Skaldman, I., Oyffe, I., Finkel, B., Sigal, M., et al.Flashback and hallucinogen persisting perception disorder: clinical aspects and pharmacological treatment approach. Isr. J. Psychiatry Relat. Sci. 2002; 39: 9299Google ScholarPubMed
Niveau, G.Flash-back cannabique, un cas medico-légal. Encephale 2002; 28: 7779Google Scholar
Pierrot, M., Josse, P., Raspiller, M.F., Goulmy, M., Rambourg, M.O., Manel, J., et al.Intoxications par champignons hallucinogènes. Ann. Med. Intern. (Paris) 2000; 151: B16B19Google Scholar
Vollenweider, F.X., Geyer, M.A.A systems model of altered consciousness: integrating natural and drug-induced psychoses. Brain Res. Bull. 2001; 56: 495507CrossRefGoogle ScholarPubMed
Young, C.R.Sertraline treatment of hallucinogen persisting perception disorder. J. Clin. Psychiatry 1997; 58: 85CrossRefGoogle ScholarPubMed
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