Data for short and long-term prothrombotic biomarkers after cryoballoon and radiofrequency ablation

Data presented in this article are supplementary analyzed tables and individual raw data to our research article entitled “Short and long-term changes in platelet and inflammatory biomarkers after cryoballoon and radiofrequency ablation (Bin Waleed K et al., 2019) [1]”. These supplementary analyzed tables and individual raw data included platelet activation biomarkers [P-selectin (CD62P), CD40 ligand (CD40L), platelet factor-4 (PF-4), mean platelet volume (MPV), platelet-leukocyte ratio (P-LCR), and platelet distribution width (PDW)]; and inflammatory biomarkers [high sensitivity CRP (hs-CRP) and interleukin-6 (IL-6)] after cryoballoon (CB) and radiofrequency (RF) ablation. The provided raw data are intended to show the difference at short and long-term in platelet and inflammatory biomarkers values between CB and RF ablation.


Data in brief
[high sensitivity CRP (hs-CRP) and interleukin-6 (IL-6)] after cryoballoon (CB) and radiofrequency (RF) ablation. The provided raw data are intended to show the difference at short and long-term in platelet and inflammatory biomarkers values between CB and RF ablation.

Data
The contents of data are platelet and inflammatory biomarkers values at baseline and 18e24h postablation, and at baseline and 6 Months post-ablation between cryoballoon (CB) and radiofrequency (RF) ablation as shown in Table 1 and Table 2 respectively; as well as individual raw data shown in supplementary excel sheet.

Subject area
Cardiology-Atrial fibrillation More specific subject area Cryoballoon versus radiofrequency ablation impact on platelet and inflammatory biomarkers Type of data Analyzed tables and individual raw data How data was acquired Platelet and inflammatory biomarkers were measured from plasma, whole blood, and serum collected at baseline (before procedure), 18e24h and 6-Months postablation in paroxysmal atrial fibrillation patients those who underwent first time cryoballoon and radiofrequency ablation.

Experimental features
Prospective, observational randomized cohort to evaluate the short and long-term changes in platelet and inflammatory biomarkers after cryoballoon and radiofrequency ablation Data source location The Value of the data Comparisons of platelet and inflammatory biomarkers after cryoballoon versus radiofrequency ablation in paroxysmal atrial fibrillation patients in both the short-and long-term. Differences in platelet biomarkers between the two ablation strategies may influence decision-making for AF ablation in the future. These raw data will be value for future studies while evaluating prothrombotic biomarkers after cryoballoon and radiofrequency ablation in paroxysmal atrial fibrillation.

Experimental design, materials and methods
The data was collected from 58 symptomatic paroxysmal atrial fibrillation (AF) defined according to expert consensus statement [2] those who undergone first-time CB (n ¼ 29) and RF (n-29) ablation (September 2016eDecember 2017) at the First Affiliated Hospital of Dalian Medical University as previously described [1e4].
SPSS 23 (IBM) was used for all statistical analyses with a p-value 0.05 considered as statistically significant. Comparison of biomarkers between CB and RF groups was performed using the independent t-test or Mann-Whitney-U test at baseline, 18e24h and 6-Months postablation as appropriate. The paired t-test or Wilcoxon signed rank test was used for repeated measurements from baseline to 18e24h or 6-Months postablation in both groups.