Data on modeling of UV/Na2S2O8/FeS2 process in amoxicillin removal using Box-Behnken methodology

Among the pharmaceutical compounds, antibiotics have been paid specific consideration, due to their acute and chronic toxic effects on organisms. Amoxicillin (AMX) is used widely for treatment of bacterial infections. About 80% of amoxicillin excreted unchanged and enters the aquatic environment through different routes including disposal of municipal wastewaters, hospital wastewaters and farm wastewaters. In this study degradation of amoxicillin by UV/Na2S2O8/FeS2 process was evaluated. According to the results, the R-squared and adjusted R-squared were 0.9877 and 0.9828, respectively. The AMX removal efficiency was 93% at optimum conditions. Thus, UV/Na2S2O8/FeS2 process is a useful process for amoxicillin removal.


a b s t r a c t
Among the pharmaceutical compounds, antibiotics have been paid specific consideration, due to their acute and chronic toxic effects on organisms. Amoxicillin (AMX) is used widely for treatment of bacterial infections. About 80% of amoxicillin excreted unchanged and enters the aquatic environment through different routes including disposal of municipal wastewaters, hospital wastewaters and farm wastewaters. In this study degradation of amoxicillin by UV/Na 2 S 2 O 8 /FeS 2 process was evaluated. According to the results, the R-squared and adjusted R-squared were 0.9877 and 0.9828, respectively. The AMX removal efficiency was 93% at optimum conditions. Thus, UV/Na 2 S 2 O 8 /FeS 2 process is a useful process for amoxicillin removal. &

Value of data
The synthesized catalyst has properties include earth abundant, low cost, high absorption coefficient and good photocatalytic activity. Also, pyrite catalyst is reusable.
This research shows a statistical method (Box-Behnken design) to optimize AMX removal from aqueous solution.
The obtained data will be appropriate for AMX removal from water and wastewater.

Data
The level of variables and their codes are shown in Table 1. For optimization of UV/Na 2 S 2 O 8 /FeS 2 process, Box-Behnken design (BBD) was applied as a response surface method [1][2][3]. The adequacy of the model was checked using analysis of variance (ANOVA) ( Table 2). P-values o 0.05 showed that the model is statistically significant [4]. Five variables (initial AMX concentration, pyrite dose, per sulfate concentration, time and pH) had linearly significant effect with p-value o 0.05. The R-Squared value (0.9828) is close to adjusted R-squared (0.9877) implying high importance of the model [5]. The diagrams of normal probability of the studentized residuals and the predicted against experimental values are shown in Figs. 1 and 2, respectively. Fig. 3 shows the interaction effects of variables on AMX removal efficiency. According to the results, a quadratic equation between dependent variable (AMX removal %) and independent variables was obtained as follows: Table 1 Levels of independent variables and experimental range in Box-Behnken design.

Factors
Range and level

Catalyst preparation
Firstly, pyrite rock sample by a ceramic mortar was milled and for 5 min in ethanol (95%) was ultra-sonicated. For removal of impurities was washed with 1 M nitric acid, rinsed with deionized water and ethanol, respectively. Subsequently, pyrite was dried at 30°C. Finally, pyrite was sieved (80 mm) [6].

Determination of AMX concentration
The AMX concentration of all samples was measured by A High Liquid Performance Chromatography (HPLC, CE4200-cecil, England). The equation below was applied for obtaining the removal efficiency (ƞ %) as follows [7][8][9]: Where, C 0 is the initial concentration and C t is residual concentration of AMX.

Box-Behnken design experiments
The experiments designed by Design-Expert software (version 7), based on Box-Behnken design (BBD) and total experiments were 46 runs. BOX-Behnken design was used to analyze five parameters i.e. pH, concentration of per sulfate, Fe S 2 concentration, contact time and initial AMX concentration on AMX removal efficiency and removal optimum conditions.
Funding sources