Data on association between QRS duration on prehospital ECG and mortality in patients with confirmed STEMI

Data presented in this article relates to the research article entitled “Association between QRS duration on prehospital ECG and mortality in patients with suspected STEMI” (Hansen et al., in press) [1]. Data on the prognostic effect of automatically recoded QRS duration on prehospital ECG and presence of classic left and right bundle branch block in 1777 consecutive patients with confirmed ST segment elevation AMI is presented. Multivariable analysis, suggested that QRS duration >111 ms, left bundle branch block and right bundle branch block were independent predictors of 30 days all-cause mortality. For interpretation and discussion of these data, refer to the research article referenced above.


Specifications
Health science More specific subject area

Cardiology
Type of data Table, figures How data was acquired

Prospective observational
Data format Analyzed Experimental factors Duration of QRS interval in ECG.

Experimental features
In consecutive patients with confirmed STEMI were prospectively included. QRS duration was registered from automated QRS measurement on the prehospital ECG that was send to the STEMI center where treatment was decided. Patients were divided according to quartiles of QRS duration. Primary endpoint was allcause 30-day mortality. Predictors of all-cause mortality were assessed using Cox proportional hazards analysis.

Data source location
Copenhagen and Odense, Denmark

Data accessibility
The data are available with this article Value of the data Data show that short term mortality is significantly higher in patients with suspected STEMI compared to those with confirmed STEMI QRS duration is an independent predictor of short term mortality in patients with confirmed STEM

Data
QRS duration has previously shown association with mortality in patients with acute myocardial infarction treated with thrombolytics. Less is known of the prognostic value of QRS duration on prehospital ECG in patients with STEMI in an contemporary population. These data are based on prospective assessment of all patients with confirmed STEMI where an prehospital ECG was available that were referred to two high volume primary PCI centers in Denmark [1].

Study population
Patients admitted with suspected STEMI were consecutively enrolled at the Heart Center, Rigshospitalet, Copenhagen from March 2015 to March 2016 and at the Department of Cardiology at Odense University Hospital Denmark from October 2015 to August 2016. Patients were excluded, if prehospital ECG was determined without significant ST segment elevation. Further, self-presenters and patients without prehospital ECG were excluded (Fig. 1).

Pre-hospital ECG
Standard 12 lead ECG was recorded by EMS using a LIFEPAK® 15 monitor/defibrillator (Physio-Control, Inc. Redmond, WA, USA) at a paper speed of 25 mm/s. All prehospital ECGs were later accessed by the medical record system and the automatically measured QRS duration was registered for this study together with presence of RBBB or LBBB. STEMI was identified on ECG as ST-segment elevation at the J-point Z0.1 mV (mV) in two contiguous leads, other than in leads V2−V3 where following cut-points applied: Z0.2 mV in men Z40 years, Z 0.25 mV in men o40 years and

Statistics
Data was analyzed using SPSS (IBM Statistics, Version 21.0). QRS duration was not Gaussian distributed thus the cohort was divided into quartiles of QRS duration ( o89 ms, 89-98 ms, 99-111 ms and 4111 ms).
All-cause mortality was assessed using Cox proportional hazard model to determine the association of QRS duration with mortality. The Kaplan Meier estimate of all-cause mortality was then calculated and plotted according to quartiles of QRS duration. For Cox proportional hazards analyses QRS duration was analysed as a categorical variable with the first quartile ( o89 ms) serving as reference. In the Cox analysis patients with LBBB and RBBB were analysed separately, accordingly the group designated QRS duration 4111 ms constituted patients with QRS duration 112-120 ms and those with unspecific conduction delay. In order to assess the value of QRS duration in prehospital triage, a Cox model based on prehospital variables (age, gender, systolic blood pressure, history of