Data on copper level in the blood of patients with normal and abnormal angiography

In this data article, we measured the levels of copper in the blood of patients undergoing coronary angiography. The samples were taken from patients with cardiovascular disease in Bushehr׳s university hospital, Iran. Patients were divided in two groups: normal angiography and abnormal angiography. After the chemical digestion of samples, the concentration levels of Cu in both groups were determined by using inductively coupled plasma optical spectrometry (ICP-OES).


a b s t r a c t
In this data article, we measured the levels of copper in the blood of patients undergoing coronary angiography. The samples were taken from patients with cardiovascular disease in Bushehr's university hospital, Iran. Patients were divided in two groups: normal angiography and abnormal angiography. After the chemical digestion of samples, the concentration levels of Cu in both groups were determined by using inductively coupled plasma optical spectrometry (ICP-OES

Value of the data
The data can be used in other studies to determine trace elements in the blood. The data can be used to evaluate the effect of trace elements on heart function. The data can be used for further studies on the trace element effects on other human organs as well as the possible role of trace elements in preventing diseases.

Data
We measured concentration levels of Cu in blood samples from patients with cardiovascular disease. General data on patients involved in present study is shown in Table 1. The concentration levels of Cu in patients with normal angiography were in the range of 24.01-135.76 mg/dL with a mean concentration level of 54.14 mg/dL. The concentration levels of Cu in patients with abnormal angiography were in the range of 33.6-221.3 mg/dL with a mean concentration level of 60.9 mg/dL ( Table 2). Chi-Square analysis also showed that between all characteristics shown in Table 1, only age had statistically significant relationship with angiography type (p-value ¼ 0.033).

Experimental design, materials and methods
Blood samples were taken from a total of 120 patients, including the patients with normal angiography (N ¼60) and patients with abnormal angiography (N ¼ 60). These individuals were randomly selected from cardiovascular patients undergoing coronary angiography, at university heart hospital of Bushehr. ECG, echo and angiography were performed for both groups. These who had normal ECG, echo and normal angiography, were placed in the control group, and so people with ECG, echo and abnormal angiogram were classified in the category of abnormal. After sampling, the blood serum was isolated by centrifuge. Then they were stored at À80°C until final analysis. For digestion of samples, 2.5 ml of serum sample was mixed with 2 ml of HNO 3 and 1 ml of H 2 O 2 . The resulting mixture was placed in an oven for 2 h at 50°C. After that, 1 ml of concentrated nitric acid and a few drops of H 2 O 2 were added to the solution. Then solution was placed on a hot plate, until clear solution was obtained. The resulting clear solution was cooled down at room temperature and 5 ml HNO 3 0.1 N, was added and a volume of 50 ml from sample was prepare by using deionized water [1]. After chemical digestion and preparation, the samples were read by using ICP-OES [2][3][4][5].

Acknowledgments
The authors are grateful to Bushehr University of Medical Sciences for their financial support (Grant no 20/71/7151) and the laboratory staff of the Environmental Health Engineering Department for their cooperation. The funder had no role in study design, data collection and analysis, or preparation of the manuscript.

Transparency document. Supplementary material
Transparency data associated with this article can be found in the online version at http://dx.doi. org/10.1016/j.dib.2016.08.021. Table 2 Mean, maximum and minimum concentration level (mg/dL) of Cu in patient with normal angiography and abnormal angiography.

Cu level in blood samples
Normal angiography Abnormal angiography