Data on amputation free survival of patients with lower limb peripheral artery disease classified according TASC II classification and a new crural index

The results of amputation free survival (AFS) of a cohort of 887 caucasian patients is shown. The data is based on further analyses of data presented in Jalkanen et al. (2016) [1]. The 36-month amputation free survival of patients divided in new crural vessel disease classification (Crural Index), aortoiliac TASC II classification, femoropopliteal TASC II classification and most severe segment is presented. Also, in depth demographic data is presented for each Crural Index group Jalkanen et al., 2016 [1].


a b s t r a c t
The results of amputation free survival (AFS) of a cohort of 887 caucasian patients is shown.
The data is based on further analyses of data presented in Jalkanen et al. (2016) [1]. The 36-month amputation free survival of patients divided in new crural vessel disease classification (Crural Index), aortoiliac TASC II classification, femoropopliteal TASC II classification and most severe segment is presented. Also, in depth demographic data is presented for each Crural Index group Jalkanen et al., 2016 [1]. & 2016 The Authors. Published by Elsevier Inc. This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).

Value of the data
This is the first analyses of correlation between AFS and crural index. The data demonstrates the challenging nature of extensive crural disease. The more extensive the atherosclerosis on crural vessels is, the more interventions are needed.
Present data shows that in addition to poor survival and AFS, crural index IV is associated with conservative treatment and inability to treat.
It also provides estimation of survival and amputation free survival for TASC II classification for aortoiliac and femoropopliteal segments [2][3][4].

Data
The presented data is acquired from analysis of amputation free survival and extent of atherosclerosis in crural vessels of PAD patients. Patient cohort was analysed according to widely used classification (TASC II) [2][3][4] and a new classification for the crural vessels [1]. The Kaplan-Meier curves for AFS are shown in Fig. 1A and B. Table 1A-E presents the mean AFS 7 SE    Table 3.

Experimental design, materials and methods
The data is based on 887 consecutive patients admitted to the Department of Vascular Surgery at the Turku University Hospital (Turku, Finland) either for diagnostic DSA or for endovascular treatment of PAD from January 1st 2009 to July 30th 2011. All patients were included regardless of earlier PAD history. Deaths and amputations within the patient cohort were registered for the first 36-months, which was the cut-off point for follow-up.

DSA analysis
The index classification was as described in TASC II for aorto-iliac and femoro-popliteal segments. Aorto-iliac and femoro-popliteal segments TASC II classification A-D, (coded as 1-4) were for the statistical analyses. For the crural region, all three vessels were first analysed separately and a Crural Index was formed accordingly (see for further description [1]). In order to assess Table 3 Mean estimated survival during 36-months follow-up, SE and 95% CI presented in the table for A) Aorto-iliac (AI), B) Femoropopliteal (FP), C) Crural (Cr) grades I-IV, D) Localization of significant atherosclerotic lesion, E) The most severe atherosclerotic segment. Log-rank test shown on the left row of the different vascular segments against each other, each patient was assigned into a specific group of disease localisation: 1) aorto-iliac, 2) femoro-popliteal or 3) crural, based on which 0-IV rating gave the highest number.

Statistical analyses
All statistical analyses were performed using the IBM SPSS version 22 statistics program. Continuous variables were expressed as mean 7 standard error (SE). Survival analyses were assessed by Kaplan-Meier curves and Log-rank statistics.