Antimicrobial Susceptibility StudiesFirst report of Escherichia coli co-producing NDM-1 and OXA-232
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Cited by (14)
First case of bloodstream infection caused by Mixta hanseatica sp. nov., a novel species within the Mixta genus of the Erwiniaceae family
2023, New Microbes and New InfectionsDistribution of β-lactamases and emergence of carbapenemases co-occurring Enterobacterales isolates with high-level antibiotic resistance identified from patients with intra-abdominal infection in the Asia–Pacific region, 2015–2018
2022, Journal of Microbiology, Immunology and InfectionCitation Excerpt :The co-occurrence of NDM-1/OXA-232 was mainly found in K. pneumoniae, with isolated cases in different countries.32–36 A sporadic case of E. coli harboring both NDM-1/OXA-232 was reported.37 In the absence of selective pressure, plasmids generally impose a fitness cost to host bacteria.
Successful control of the first OXA-48 and/or NDM carbapenemase-producing Klebsiella pneumoniae outbreak in Slovenia 2014–2016
2019, Journal of Hospital InfectionCitation Excerpt :Co-production of carbapenemases of different classes can complicate treatment as next-generation β-lactam/β-lactamase inhibitor combinations currently available are only suitable for serine carbapenemase and are inactive against metallo-β-lactamases. Co-production of OXA-48 and NDM, which can present a serious treatment challenge, has been described in several studies [22–29]. Slovenia was one of the few countries where CPEs occurred only sporadically and until October 2014 it remained at epidemiological stage 1 [3].
Ordering the mob: Insights into replicon and MOB typing schemes from analysis of a curated dataset of publicly available plasmids
2017, PlasmidCitation Excerpt :PacBio sequencing technology has clearly been a key driver of the increase in complete plasmid sequences since 2014 (Fig. 1; data prior to 2014 not shown due to a lack of annotation for sequencing technology). The first complete plasmids sequenced using Oxford Nanopore technology were added in June 2016 (Both et al., 2016) and this technology will likely drive further expansion in availability of complete plasmid sequences in future. Sequence topology annotation (circular/linear) was an unreliable indicator of complete plasmid sequences, with 57 of the 2097 curated plasmids annotated as ‘linear’.
Characteristics of Enterobacteriaceae Isolates Coharboring Distinct Carbapenemase Genes
2017, Infection Control and Hospital Epidemiology
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These authors contributed equally to this work.