Current Biology
Volume 21, Issue 1, 11 January 2011, Pages R27-R30
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Actin Motility: Formin a SCAry Tail

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Summary

A new biochemical analysis has revealed that the Rickettsia bacterial protein Sca2 — recently shown to be essential for virulence and actin-dependent motility — assembles actin filaments using a mechanism that functionally resembles the processive elongation tactics used by formins.

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