Data and code availability
The full transcriptomics data are available on GeneNetwork.org under Species: mouse, Group: BXD NIA Longevity Study, Type: Liver mRNA, and Dataset: UTHSC BXD Harvested Liver RNA-Seq (Aug18) RPKM Log2. Raw mass spectrometry data for proteomics are available on ProteomeXchange (Vizcaino et al., 2016), PRIDE: PXD009160. Raw mass spectrometry data for metabolomics are available on MassIVE: MSV000081441. All processed data, for the omics layers and the phenotypes, are available in a “ready to use” Data S1, which is the version of the data that was used to generate the figures. All code required for generating the figures, along with some helper files, are included in Data S2.