Cell
Volume 153, Issue 2, 11 April 2013, Pages 480-492
ResourceMethylation-Dependent and -Independent Genomic Targeting Principles of the MBD Protein Family
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Graphical Abstract
Highlights
► Identification of genome-wide binding preferences for MBD proteins and isoforms ► Majority of binding scales linearly with local DNA methylation density ► MBD proteins show additional, direct, and indirect binding to unmethylated sites ► MBD2 interaction with NuRD is restricted to unmethylated sites
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Present address: Department of Biomedicine, University of Basel, Mattenstrasse 28, 4058 Basel, Switzerland
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Present address: Department of Systems Biology, Harvard Medical School, 200 Longwood Avenue, Boston, MA 02115, USA
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