Cell
Volume 137, Issue 2, 17 April 2009, Pages 191-196
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Essay
The BAR Domain Superfamily: Membrane-Molding Macromolecules

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Membrane-shaping proteins of the BAR domain superfamily are determinants of organelle biogenesis, membrane trafficking, cell division, and cell migration. An upsurge of research now reveals new principles of BAR domain-mediated membrane remodeling, enhancing our understanding of membrane curvature-mediated information processing.

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Present address: Department of Cellular and Molecular Pharmacology, University of California, San Francisco and California Institute for Quantitative Biosciences, San Francisco, CA 94158, USA