How Do the ASTRO Consensus Statement Guidelines for the Application of Accelerated Partial Breast Irradiation Fit Intraoperative Radiotherapy? A Retrospective Analysis of Patients Treated at the European Institute of Oncology: Leonardi MC, Maisonneuve P, Mastropasqua MG, et al (European Inst of Oncology, Milan, Italy) Int J Radiat Oncol Biol Phys 83:806-813, 2012§
Section snippets
Purpose
To verify how the classification according to the American Society for Therapeutic Radiation Oncology (ASTRO) consensus statement (CS) for the application of accelerated partial breast irradiation (APBI) fits patients treated with intraoperative radiotherapy with electrons (ELIOT) at a single institution.
Methods and Materials
The study included 1,822 patients treated with ELIOT as the sole radiation modality outside of a clinical trial at the European Institute of Oncology after breast-conserving surgery for
Commentary
Intraoperative radiotherapy (IORT) has not become a standard treatment option for breast cancer patients in the United States for a number of reasons, including the prolonged operating room times needed for its delivery, the risk of improper patient selection based on incomplete pathologic data available at the time of treatment, and the relatively short-term follow-up data. The ASTRO suitability criteria were not designed to be used for IORT, but there is still a tendency to apply the