Heterogeneity of chemical composition of lipid droplets in endothelial inflammation and apoptosis
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Graphical abstract
Abbreviations
AA
arachidonic acid
Ang II
angiotensin II
ATGL
adipose triglyceride lipase
COX
cyclooxygenase
EC
endothelial cell
FADD
FAS-associated death domain protein
FasL
Fas ligand
FBS
fetal bovine serum
HMEC-1
human microvascular endothelial cells
hTNF-α
human TNF-α
ICAM-1
intercellular cell adhesion molecule 1
IL-1β
interleukin-1β
LD
lipid droplet
LPS
lipopolysaccharides
mTNF-α
murine TNF-α
NF-kB
nuclear factor kappa-light-chain-enhancer of activated B cells
NO
nitric oxide(II)
PAI-1
plasminogen activator inhibitor-1
PECAM-1
platelet endothelial cell adhesion molecule
PGI2
prostacyclin I2
RI
Raman imaging
RIP1
receptor interacting protein 1
ROS
reactive oxygen species
sICAM-1
soluble intercellular cell adhesion molecule 1
sTM
soluble trombomodulin
sVCAM-1
soluble vacular cell adhesion molecule 1
TM
thrombomodulin
TNF-α
tumour necrosis factor
TNFR1
TNF receptor 1
TRADD
TNFR1-associated death domain protein
VCAM-1
vascular cell adhesion molecule 1
vWF
von Willebrand factor
Keywords
Endothelium
Inflammation
Apoptosis
Lipid droplets
Raman imaging
Fluorescence imaging
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