Case report
Nodular Lymphoid Hyperplasia of the Lung: A Very Rare Disease Entity

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Nodular lymphoid hyperplasia of the lung is an uncommon disease that is considered to be a benign lesion of a polyclonal lymphoid proliferation. Because of its rarity, little is known about the clinicopathologic characteristics of nodular lymphoid hyperplasia. Some researchers have questioned whether nodular lymphoid hyperplasias are truly reactive or are marginal zone B-cell lymphomas (low-grade lymphomas of mucosa-associated lymphoid tissue) mimicking reactive lymphoid processes. We present the case of a 67-year-old woman with nodular lymphoid hyperplasia of the lung and discuss the current knowledge concerning nodular lymphoid hyperplasias.

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Comment

In 1983, Kradin and Mark [4] first suggested the term nodular lymphoid hyperplasia, which is thought to be a benign lesion consisting of a reactive lymphoid proliferation. The cause of NLH is unclear. NLH has recently been recognized in the histologic typing of lung and pleural tumors by the WHO [3]. NLH can develop at a wide variety of sites other than the lung [5]. Although NLH has been considered to be a synonym of “pseudolymphoma,” as initially proposed by Saltzstein in 1963 [2],

References (8)

  • R.L. Kradin et al.

    Benign lymphoid disorders of the lung, with a theory regarding their development

    Hum Pathol

    (1983)
  • S.L. Abbondanzo et al.

    Nodular lymphoid hyperplasia of the lung: a clinicopathologic study of 14 cases

    Am J Surg Pathol

    (2000)
  • S.L. Saltzstein

    Pulmonary malignant lymphomas and pseudolymphomas: classification, therapy, and prognosis

    Cancer

    (1963)
  • W.D. Travis et al.

    Histological typing of lung and pleural tumors, World Health Organization international histological classification of tumors

    (1999)
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