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Lady Windermere Syndrome

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Case Presentation

A 60-year-old female with chronic bronchitis was admitted with a 4-day history of fever and increased baseline cough and sputum production. Physical examination demonstrated diffuse wheezing and bibasilar rales. Chest radiograph revealed hyperexpansion, multiple nodular and linear opacities and calcifications in the right middle lobe and lingula (Figure 1). Computed tomography revealed bronchiectasis of the right middle lobe and lingula (Figure 2). Sputum analysis revealed a polymicrobial

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    Citation Excerpt :

    Non-tuberculous mycobacteria, primarily caused by Mycobacterium avium complex and Mycobacterium abscessus, lung infections are found in immunocompromised and otherwise functionally compromised lungs. It is particularly serious in cystic fibrosis patients and a portion of the elderly population identified in Lady Windermere Syndrome [47–49]. The disease manifests as extracellular biofilms associated with bronchiectasis and intracellular disease in lung macrophages [50].

Both authors claim no conflicts of interest or disclosures. This has not been submitted or presented elsewhere in any form.

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