Prognostic significance of renal insufficiency in patients presenting with acute coronary syndrome (the Prospective Multicenter SYCOMORE study)

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This prospective, multicenter, observational study was designed to assess the in-hospital prognostic importance of renal insufficiency among patients presenting with acute coronary syndrome (ACS). One third of patients with ACS presented with renal insufficiency. After adjustment for potential confounders, decreasing renal function was independently associated with in-hospital death, bleeding, and contrast-induced nephropathy.

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Acknowledgment

We are thankful to C. Michael Gibson, MD, for his expert advice and for his editorial review of the manuscript.

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This registry was supported by a grant from MSD Pharmaceuticals, Paris, France.

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