American Journal of Obstetrics and Gynecology
AbstractsEffect of the severity of pulmonary stenosis on pregnancy outcomes-a case control study
Section snippets
Objective
To evaluate pregnancy outcomes in patients with mild and severe pulmonary stenosis (PS) (Peak gradient of less than 50 mm Hg across the pulmonary valve is categorized as mild PS, and more than 50 as severe).
Study design
Case-control cohort study of 17 cases with PS in pregnancy from 1995-2003. The control group was matched by age, ethnicity, obstetrical history, and the year of delivery. Maternal NYHA functional class at baseline and during pregnancy, fetal and neonatal outcomes including birth weight, placental weight, gestational age at delivery, and Apgar scores were compared between the two groups.
Results
Eleven patients were in NYHA functional class I, and 6 in class II at the time of presentation. All patients remained stable during pregnancy except one who deteriorated from NYHA functional class I to II. There was no statistically significant difference in fetal/neonatal outcomes. Data are presented as mean ± SD in Tables I and II.
Conclusion
In contrast to mitral and aortic stenosis, the severity of PS does not adversely impact maternal or fetal/neonatal outcomes.Empty Cell Subjects Controls P value Birth weight (g) 3278 ± 474 3360 ± 432 .73 Placental weight (g) 648 ±184 693 ± 421 .83 Gestational age at delivery (wk) 38.4 ± 1.9 39.3 ± 1.2 .07 Median Apgar score 1 min 9 9 3.79 Median Apgar score 5 min 9 9 1.37 Empty Cell Mild PS Severe PS P value Birth wt (g) 3198 ± 569 3192 ± 553 .99 Placental wt (g) 681 ± 205 597