Case report
Cytomegalovirus retinitis after treatment with topical difluprednate in an aphakic eye of an immunocompetent patient

https://doi.org/10.1016/j.ajoc.2019.100552Get rights and content
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Abstract

Purpose

To report a case of an immunocompetent 64-year-old man who developed cytomegalovirus (CMV) retinitis after using topical difluprednate.

Observations

A 64-year-old man with type 2 diabetes developed hemorrhagic retinitis while using topical difluprednate after penetrating keratoplasty. Polymerase chain reaction of the vitreous was positive for CMV DNA. Complete blood count was within normal limits and 4th generation human immunodeficiency virus assay was negative. The retinitis resolved with oral valgancyclovir and intravitreal foscarnet injections.

Conclusion and importance

CMV retinitis may occur after topical difluprednate in an immunocompetent patient.

Keywords

Cytomegalovirus retinitis
Topical steroid
Difluprednate

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