Cancer Cell
Volume 1, Issue 1, February 2002, Pages 19-30
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Review
A matter of life and death

https://doi.org/10.1016/S1535-6108(02)00024-7Get rights and content
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Abstract

We propose that deregulation of proliferation, together with a reduction in apoptosis, creates a platform that is both necessary and can be sufficient for cancer. The secondary traits of diverse neoplasms are a consequence of cell proliferation, tissue expansion, and other outcomes of this platform.

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