Giant ossifying fibroma. Case report on a bimaxillary presentation

doi:10.1016/S0901-5027(05)80226-7

International Journal of Oral and Maxillofacial Surgery

Volume 21, Issue 4, August 1992, Pages 233-235

https://doi.org/10.1016/S0901-5027(05)80226-7 Get rights and content

Abstract

Ossifying fibroma is a slow-growing, benign neoplasm, but some lesions behave aggressively, reaching massive proportions, thus demanding special treatment. The following case report holds particular interest, because of the simultaneous occurrence of an active ossifying-cementifying fibroma in the maxilla and mandible with the maxillary lesion attaining enormous size.

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Cited by (28)

Bilateral ossifying fibroma affecting the jaws: Literature review, rare case report
2023, International Journal of Surgery Case Reports
Ossifying fibroma (OF) is a benign lesion could occur in different areas of the body and contain fibers, cells and non-organic materials in non specific amounts. It is growing could be slow or rapid and according to this an array of treatment options must be considered to avoid future complications.
In this article, we present a case report of a 40-year-old female patient who visited the dentist with the intention of having a normal check up. Bilateral lesion was observed in the mandible, the patient had no medical history of trauma. The lesion was removed surgically and analyzed histologically and the result was ossifying fibroma in both sides.
Ossifying fibroma is a rare tumor to be found in the oral cavity, and the family of fibro-osseous lesions (FOLs) has in general the same pathologic features and differ from each other in clinical view so the definitive diagnosis is based on mixture of all these elements. The treatment is complete surgical excision.
11 cases were discovered and archived since 1968 until now, the distribution of cases is nearly equal in the oral cavity, and the infection of females is higher than males.
Ossifying fibroma of the ethmoid sinus with orbital invasion: A case report
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Bilateral psammomatoid ossifying fibroma: A case report and review of the literature
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Citation Excerpt :
Ossifying fibroma can present as a solitary lesion or as multiple lesions, though the occurrence of multiple lesions is very rare. To the best of our knowledge, only 12 cases of multiple ossifying fibroma have been reported, the details for which are summarized in Table 1.4,7-17 The present case was unique, as it was the first case of a bilateral psammomatoid ossifying fibroma involving the maxillary arches in a patient to be reported.
Synchronous ossifying fibromas of the jaws: A review
2012, Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology
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Yih et al. (1989)25 reported multiple familial ossifying fibromas as a heritable disorder. Khanna and Andrade (1992)22 reported a patient who had 2 cemento-ossifying fibromas involving the mandible and maxilla, and the maxillary lesion achieved enormous size. Their case is similar to the present case.
According to the World Health Organization, it is proposed that benign fibro-osseous lesions be divided into 3 categories, including fibrous dysplasia, ossifying fibroma (OF), and osseous dysplasia. OF arises from the periodontal ligament, which contains multipotential cells. These benign tumors may become large and aggressive. Slow growth and lack of symptoms are the cardinal features. OF tends to occur in the second and third decades of life, with predilection for women and for the mandibular premolar-molar area. The method of treatment used for large or rapidly expanding lesions is surgical removal (enucleation). Rarely, OFs occur multifocally. We report a 20-year-old man with synchronous OFs of his maxilla and mandible and review other synchronous cases reported. Such lesions can be properly diagnosed and treated by correlating radiographic, clinical, surgical, and histopathologic findings.
Clinicopathologic conference: Multiquadrant expansile fibro-osseous lesion in a juvenile
2012, Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology
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These lesions generally tend to be solitary, with maxilla and paranasal sinuses being the most commonly involved regions.13 Although cases of multiple juvenile ossifying fibroma have been reported previously,14,15 there have been no reports of simultaneous involvement of all the 4 quadrants, as in this case. Juvenile trabecular ossifying fibroma and juvenile psammomatoid ossifying fibroma are 2 histologic variants of JOF.13
This paper intends to present clinical, radiologic, and histopathologic features of a case of gigantiform cementoma manifesting in a 14-year-old boy, without any familial involvement. He has been followed for 3 years. Further cases from the literature have been reviewed that confirm a similar clinicopathologic picture. This is the first case report that describes “non-familial gigantiform cementoma” after the World Health Organisation's classification of 2005.
Bilateral central ossifying fibroma affecting the mandible: Report of an uncommon case and critical review of the literature
2011, Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology and Endodontology
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Ossifying fibroma is mainly diagnosed between the second and fourth decades of life, with women being affected more frequently than men.1-3 To the best of our knowledge, multiple synchronous central OFs are rare events, with only 10 previously reported cases.8-17 The main features of these cases are summarized in Table I.

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Giant ossifying fibroma. Case report on a bimaxillary presentation

Abstract

Oral Surg

Oral Surg

Oral Surg

Oral Surg

Br J Oral Surg

J Oral Maxillofac Surg

Int J Oral Maxillofac Surg

Oral Surg

Central ossifying fibroma of the jaws

Oral Surg

Giant central ossifying fibroma of the mandible. Report of case

J Oral Surg

Periodontal ligament fibroblasts, pre-osteoblasts and pre-chondrocytes express receptors for epidermal growth factor in vivo

J Periodont Res

Ossifying fibroma. Report of case

J Oral Surg

Benign fibro-osseous jaw lesions of periodontal membrane origin. An analysis of 249 cases

Cancer