Elsevier

Brain and Development

Volume 14, Issue 6, November 1992, Pages 396-400
Brain and Development

Down syndrome complicated by brain tumors: Case report and review of the literature

https://doi.org/10.1016/S0387-7604(12)80347-0Get rights and content

This report concerns a 24-year-old male patient with Down syndrome, complicated by a benign but true neoplastic lesion of a differentiated papilloma of the choroid plexus which simultaneously displayed a dysgenetic character. A review of the literature revealed a lack of single case reports of Down syndrome with brain tumors, which may reflect chance occurrence; however, the brain tumors in Down syndrome patients are characterized by their dysontogenetic or dysgenetic character.

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