Elsevier

Burns

Volume 24, Issue 5, August 1998, Pages 481-483
Burns

Scientific and clinical paper
Citric acid treatment of severe electric burns complicated by multiple antibiotic resistant Pseudomonas aeruginosa

https://doi.org/10.1016/S0305-4179(98)00052-7Get rights and content

Abstract

A case of severe electric burns complicated by multiple antibiotic resistant Pseudomonas aeruginosa not responding to various antibiotics administered systemically is presented. Citric acid (3%) was used successfully to eliminate Pseudomonas aeruginosa from burn wounds and infection was completely controlled in 14 days. Citric acid treatment is evidently of value in the clinical control of burn wound colonization caused by difficult strains of Pseudomonas aeruginosa.

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    It also enhanced formation of healthy granulation tissue, renewal of epithelia and accelerated the healing process. The microbiological evaluation before and after the application of citric acid showed that before the application of citric acid, the pus swab collected from wound yielded P. aeruginosa in significant numbers on culture, however post-citric acid application, the repeat culture of a swab showed no growth or significant reduction in the number of P. aeruginosa counts in our studies [58–60] suggesting that citric acid helps in controlling infection effectively. The similar findings have also been observed in various other studies [68–70].

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    Application of citric acid quickly eliminated P. aeruginosa from infection site. Citric acid was found to be simple, reliable, nontoxic, effective and economical approach in the management of superficial infections caused by multiple antibiotic resistant strains of P. aeruginosa [35,36]. The salicyclic acid has also been reported effective against P. aeruginosa in a concentration of 0.5–2% and in a concentration of 0.5% has been found to be safe and inexpensive topical agent suitable for thermal burns, which are not heavily contaminated [37].

  • Simple, effective and affordable approach for the treatment of burns infections

    2010, Burns
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    In view of this, an attempt was made to develop an effective and economical approach for the treatment of burns infections using citric acid as a sole antimicrobial agent. The use of citric acid as a topical agent for effective elimination of P. aeruginosa from the burn wound has been reported [28]. Citric acid was also found effective against other bacteria isolated from various types of wound infections [29].

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    2008, Journal of Hospital Infection
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    Antimicrobial resistance is a major problem and is continuously increasing all over the world, especially in nosocomial infections. The topical use of acetic acid and citric acid for the treatment of nosocomial wound infections caused by P. aeruginosa has been reported previously.1–4 Considering multiple antibiotic resistance E. coli (MAREC) in association with chronic wound infections, an attempt was made to treat such infections with citric acid.

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